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RAB27A 抗体 (C-Term)

Cited in 5+ publications. This 兔 多克隆 anti-RAB27A antibody (Clone RB42745) specifically detects RAB27A in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881720
发货至: 中国
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Quick Overview for RAB27A 抗体 (C-Term) (ABIN1881720)

抗原

See all RAB27A 抗体
RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

适用

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宿主

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克隆类型

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多克隆

标记

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This RAB27A antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB42745
  • 抗原表位

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    AA 136-164, C-Term

    预测反应

    M, Pig, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ohbayashi, Mamishi, Ishibashi, Maruta, Pourakbari, Tamizifar, Mohammadpour, Fukuda, Parvaneh: "Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2." in: Pigment cell & melanoma research, Vol. 23, Issue 3, pp. 365-74, (2010) (PubMed).

    Meeths, Bryceson, Rudd, Zheng, Wood, Ramme, Beutel, Hasle, Heilmann, Hultenby, Ljunggren, Fadeel, Nordenskjöld, Henter: "Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations." in: Pediatric blood & cancer, Vol. 54, Issue 4, pp. 563-72, (2010) (PubMed).

    Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

    Chattopadhyay, Singh, Phukan, Purkayastha, Kataki, Mahanta, Saxena, Kapur: "Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India." in: Mutation research, Vol. 696, Issue 2, pp. 130-8, (2010) (PubMed).

    Wood, Meeths, Chiang, Bechensteen, Boelens, Heilmann, Horiuchi, Rosthøj, Rutynowska, Winiarski, Stow, Nordenskjöld, Henter, Ljunggren, Bryceson: "Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity." in: Blood, Vol. 114, Issue 19, pp. 4117-27, (2009) (PubMed).

  • 抗原

    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

    别名

    RAB27A

    背景

    The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

    分子量

    24868

    NCBI登录号

    NP_004571, NP_899057, NP_899058, NP_899059

    UniProt

    P51159

    途径

    Peptide Hormone Metabolism
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