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MMP14 抗体 (C-Term)

This anti-MMP14 antibody is a 兔 多克隆 antibody detecting MMP14 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1881546
发货至: 中国

Quick Overview for MMP14 抗体 (C-Term) (ABIN1881546)

抗原

See all MMP14 抗体
MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

适用

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宿主

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克隆类型

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多克隆

标记

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This MMP14 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41662
  • 抗原表位

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    AA 495-523, C-Term

    预测反应

    M, Pig, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human MMP14.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Sakr, Takino, Domoto, Nakano, Wong, Sasaki, Nakanuma, Sato: "GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase." in: Cancer science, Vol. 101, Issue 11, pp. 2368-74, (2010) (PubMed).

  • 抗原

    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

    别名

    MMP14

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

    分子量

    65894

    NCBI登录号

    NP_004986

    UniProt

    P50281

    途径

    Autophagy
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