GPR68 抗体 (AA 200-225)
Quick Overview for GPR68 抗体 (AA 200-225) (ABIN1881516)
抗原
See all GPR68 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-225
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预测反应
- B, H
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Gpr68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-225 amino acids from the Central region of mouse Gpr68.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 2, pp. 305-13, (2009) (PubMed).
: "Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer." in: Journal of the National Cancer Institute, Vol. 99, Issue 17, pp. 1313-27, (2007) (PubMed).
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: "Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 2, pp. 305-13, (2009) (PubMed).
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- GPR68 (G Protein-Coupled Receptor 68 (GPR68))
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别名
- Gpr68
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背景
- Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
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分子量
- 41209
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NCBI登录号
- NP_001171144, NP_001171145, NP_780702
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UniProt
- Q8BFQ3
抗原
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