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GPR68 抗体 (AA 200-225)

Cited in 2+ publications. The 兔 多克隆 anti-GPR68 antibody (ABIN1881516) specifically detects GPR68 in WB. The antibody is reactive with 小鼠 samples.
产品编号 ABIN1881516
发货至: 中国
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Quick Overview for GPR68 抗体 (AA 200-225) (ABIN1881516)

抗原

See all GPR68 抗体
GPR68 (G Protein-Coupled Receptor 68 (GPR68))

适用

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小鼠

宿主

  • 39
  • 1

克隆类型

  • 39
  • 1
多克隆

标记

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This GPR68 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 7
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    AA 200-225

    预测反应

    B, H

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Gpr68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-225 amino acids from the Central region of mouse Gpr68.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Frick, Krieger, Nehrke, Bushinsky: "Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 2, pp. 305-13, (2009) (PubMed).

    Singh, Berk, Oates, Zhao, Tan, Jiang, Zhou, Kirmani, Steinmetz, Lindner, Xu: "Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer." in: Journal of the National Cancer Institute, Vol. 99, Issue 17, pp. 1313-27, (2007) (PubMed).

  • 抗原

    GPR68 (G Protein-Coupled Receptor 68 (GPR68))

    别名

    Gpr68

    背景

    Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.

    分子量

    41209

    NCBI登录号

    NP_001171144, NP_001171145, NP_780702

    UniProt

    Q8BFQ3
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