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TIM3 抗体 (AA 167-194)

Name: TIM3 抗体 (AA 167-194)
SKU: ABIN1881402
Availability: OutOfStock

Cited in 5+ publications. This 兔多克隆 anti-TIM3 antibody (Clone RB41963) specifically detects TIM3 in WB. The antibody is reactive with 人 samples.

All lanes : Anti-HAVCR2 Antibody (Center) at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: human kidney lysates Lane 3: KG-1 whole cell lysates Lane 4: human liver lysates Lysates/proteins at 20 μg per lane. (TIM3 抗体 (AA 167-194))

All lanes : Anti-HAVCR2 Antibody (Center) at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: KG-1 whole cell lysates Lane 3: human liver lysates Lysates/proteins at 20 μg per lane. (TIM3 抗体 (AA 167-194))

HAVCR2 Antibody (Center) (ABIN1881402 and ABIN2838913) western blot analysis in T47D cell line lysates (35 μg/lane). (TIM3 抗体 (AA 167-194))

3 images

(5 references)

产品编号 ABIN1881402

发货至: 中国

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Quick Overview for TIM3 抗体 (AA 167-194) (ABIN1881402)

抗原

See all TIM3 (TIM 3) 抗体

TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This TIM3 antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB41963

Discover our top product TIM 3 Primary Antibody

抗原表位
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AA 167-194

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2.

亚型

Ig Fraction
anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (Internal Region) antibody
Verified TIM 3 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibody
TIM 3 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal TIM3-3113 unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibody
TIM 3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibody
TIM 3 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 7C8A7 unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 224-301) antibody
TIM 3 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2A7A6 unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) antibody
TIM 3 适用: 人 IHC 宿主: 兔 Monoclonal 366R unconjugated Recombinant Antibody

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) antibody
TIM 3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibody
TIM 3 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) (AA 22-202) antibody
TIM 3 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated

anti-Hepatitis A Virus Cellular Receptor 2 (TIM 3) antibody
TIM 3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1827CT151-74-68 unconjugated

应用备注

WB: 1:2000. WB: 1:2000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Cao, Zhu, Zhu, Li, Zhang, Xu, Zhang: "Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer." in: Cancer immunology, immunotherapy : CII, Vol. 59, Issue 12, pp. 1851-7, (2010) (PubMed).

Dorfman, Hornick, Shahsafaei, Freeman: "The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms." in: Human pathology, Vol. 41, Issue 10, pp. 1486-94, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Dardalhon, Anderson, Karman, Apetoh, Chandwaskar, Lee, Cornejo, Nishi, Yamauchi, Quintana, Sobel, Hirashima, Kuchroo: "Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 3, pp. 1383-92, (2010) (PubMed).

Schuurhof, Bont, Siezen, Hodemaekers, van Houwelingen, Kimman, Hoebee, Kimpen, Janssen: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, (2010) (PubMed).
抗原

TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

别名

HAVCR2

物质类

Virus

背景

CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.

分子量

33394

NCBI登录号

NP_116171

UniProt

Q8TDQ0

途径

Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints