TIM3 抗体 (AA 167-194)
Quick Overview for TIM3 抗体 (AA 167-194) (ABIN1881402)
抗原
See all TIM3 (TIM 3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 167-194
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:2000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer." in: Cancer immunology, immunotherapy : CII, Vol. 59, Issue 12, pp. 1851-7, (2010) (PubMed).
: "The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms." in: Human pathology, Vol. 41, Issue 10, pp. 1486-94, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 3, pp. 1383-92, (2010) (PubMed).
: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, (2010) (PubMed).
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Genetic variations and haplotypes in TIM-3 gene and the risk of gastric cancer." in: Cancer immunology, immunotherapy : CII, Vol. 59, Issue 12, pp. 1851-7, (2010) (PubMed).
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- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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别名
- HAVCR2
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物质类
- Virus
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背景
- CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
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分子量
- 33394
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NCBI登录号
- NP_116171
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UniProt
- Q8TDQ0
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途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
抗原
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