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p300 抗体 (pSer1834)

Name: p300 抗体 (pSer1834)
SKU: ABIN1881299
Availability: OutOfStock

This anti-p300 antibody is a 兔多克隆 antibody detecting p300 in DB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.

Dot blot analysis of E Antibody (Phospho ) Phospho-specific Pab (ABIN1881299 and ABIN2839953) on nitrocellulose membrane. (p300 抗体 (pSer1834))

1 image

(5 references)

产品编号 ABIN1881299

发货至: 中国

Datasheet as PDF

Quick Overview for p300 抗体 (pSer1834) (ABIN1881299)

抗原

See all p300 (EP300) 抗体

p300 (EP300) (E1A Binding Protein P300 (EP300))

适用

人

宿主

兔

克隆类型

多克隆

标记

This p300 antibody is un-conjugated

应用范围

Dot Blot (DB)

克隆位点

RB41431

Discover our top product EP300 Primary Antibody

抗原表位
35

11

6

5

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer1834

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300.

亚型

Ig Fraction
anti-E1A Binding Protein P300 (EP300) (AA 1-270) antibody
EP300 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 731-830) antibody
EP300 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 2065-2414) antibody
EP300 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 1351-1601) antibody
EP300 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 1-158) antibody
EP300 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) antibody
EP300 适用: 人 WB, IP, ICC, IF, ChIP, ChIP-seq 宿主: 小鼠 Monoclonal NM11 unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 2124-2397) antibody
EP300 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 731-831) antibody
EP300 适用: 人 WB, IHC, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated

anti-E1A Binding Protein P300 (EP300) (N-Term) antibody
EP300 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) antibody
EP300 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7D8A6 unconjugated

应用备注

DB: 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Zhang, Zhang, Rui, Liu: "p300-mediated acetylation stabilizes the Th-inducing POK factor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3960-9, (2010) (PubMed).

Vempati, Jayani, Notani, Sengupta, Galande, Haldar: "p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28553-64, (2010) (PubMed).

Reynoird, Schwartz, Delvecchio, Sadoul, Meyers, Mukherjee, Caron, Kimura, Rousseaux, Cole, Panne, French, Khochbin: "Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains." in: The EMBO journal, Vol. 29, Issue 17, pp. 2943-52, (2010) (PubMed).

Jang, Choi, Jeong, Lee: "Phosphorylation of p300 by ATM controls the stability of NBS1." in: Biochemical and biophysical research communications, Vol. 397, Issue 4, pp. 637-43, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
抗原

p300 (EP300) (E1A Binding Protein P300 (EP300))

别名

EP300

背景

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

分子量

264161

NCBI登录号

NP_001420

UniProt

Q09472

途径

p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size