我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

p300 抗体 (pSer1834)

There are 5+ publications for this product available. The 兔多克隆 anti-p300 antibody is suitable to detect p300 in samples from 人. It has been validated for DB.

1 image

(5 references)

产品编号 ABIN1881299

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for p300 抗体 (pSer1834) (ABIN1881299)

抗原

See all p300 (EP300) 抗体

p300 (EP300) (E1A Binding Protein P300 (EP300))

适用

人

宿主

兔

克隆类型

多克隆

标记

This p300 antibody is un-conjugated

应用范围

Dot Blot (DB)

克隆位点

RB41431

Discover our top product EP300 Primary Antibody

抗原表位
35

13

9

7

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer1834

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human EP300.

亚型

Ig Fraction
anti-E1A Binding Protein P300 (EP300) (AA 731-830) antibody
EP300 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B1 unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 2065-2414) antibody
EP300 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 1351-1601) antibody
EP300 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (N-Term) antibody
EP300 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 2283-2414) antibody
EP300 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 1-158) antibody
EP300 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) antibody
EP300 适用: 人 WB, IP, IF, ICC, ChIP, ChIP-seq 宿主: 小鼠 Monoclonal NM11 unconjugated

anti-E1A Binding Protein P300 (EP300) (AA 2124-2397) antibody
EP300 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) antibody
EP300 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-E1A Binding Protein P300 (EP300) (N-Term) antibody
EP300 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

DB: 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Zhang, Zhang, Rui, Liu: "p300-mediated acetylation stabilizes the Th-inducing POK factor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 3960-9, (2010) (PubMed).

Vempati, Jayani, Notani, Sengupta, Galande, Haldar: "p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28553-64, (2010) (PubMed).

Reynoird, Schwartz, Delvecchio, Sadoul, Meyers, Mukherjee, Caron, Kimura, Rousseaux, Cole, Panne, French, Khochbin: "Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains." in: The EMBO journal, Vol. 29, Issue 17, pp. 2943-52, (2010) (PubMed).

Jang, Choi, Jeong, Lee: "Phosphorylation of p300 by ATM controls the stability of NBS1." in: Biochemical and biophysical research communications, Vol. 397, Issue 4, pp. 637-43, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
抗原

p300 (EP300) (E1A Binding Protein P300 (EP300))

别名

EP300

背景

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

分子量

264161

NCBI登录号

NP_001420

UniProt

Q09472

途径

p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size