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EGFR 抗体 (AA 1070-1099)

Name: EGFR 抗体 (AA 1070-1099)
SKU: ABIN1881287
Availability: OutOfStock

This anti-EGFR antibody is a 兔多克隆 antibody detecting EGFR in WB. Suitable for 人. This Primary Antibody has been cited in 7+ publications.

EGFR Antibody (p) p western blot analysis in A431,Hela,HUVEC,PC-3 cell line lysates (35 μg/lane). (EGFR 抗体 (AA 1070-1099))

1 image

(7 references)

产品编号 ABIN1881287

发货至: 中国

Datasheet as PDF

Quick Overview for EGFR 抗体 (AA 1070-1099) (ABIN1881287)

抗原

See all EGFR 抗体

EGFR (Epidermal Growth Factor Receptor (EGFR))

适用

人

宿主

兔

克隆类型

多克隆

标记

This EGFR antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB11265

Discover our top product EGFR Primary Antibody

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AA 1070-1099

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1070-1099 amino acids from human EGFR.

亚型

Ig Fraction
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A6F12 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
EGFR 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR 适用: 人, 小鼠, 大鼠, Pig, 猴, Cow, 小鸡, 犬, 马, 兔, 豚鼠, Avian, Cat, 驴, 山羊, Hamster, 绵羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5E10D3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR 适用: 人, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
EGFR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Dong, Zhang, Sun, Liu, Yin, Li, Zheng, Zeng: "Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stress." in: Scientific reports, Vol. 6, pp. 36860, (2018) (PubMed).

Luo, Zhao, Shi, Feng, Chen, Li: "Induction of Apoptosis in Human Leukemic Cell Lines by Diallyl Disulfide via Modulation of EGFR/ERK/PKM2 Signaling Pathways." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 16, Issue 8, pp. 3509-15, (2015) (PubMed).

Zanardi, Yei, Lichtenstein, Tollefson, Wold: "Distinct domains in the adenovirus E3 RIDalpha protein are required for degradation of Fas and the epidermal growth factor receptor." in: Journal of virology, Vol. 77, Issue 21, pp. 11685-96, (2003) (PubMed).

Krug, Grossmann, Schuster, Freudinger, Mildenberger, Govindan, Gekle: "Aldosterone stimulates epidermal growth factor receptor expression." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 43060-6, (2003) (PubMed).

Huang, Jiang, Sorkin: "Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 43411-7, (2003) (PubMed).

He, Huang, Gentry, Chignell: "Epidermal growth factor receptor down-regulation induced by UVA in human keratinocytes does not require the receptor kinase activity." in: The Journal of biological chemistry, Vol. 278, Issue 43, pp. 42457-65, (2003) (PubMed).

Hirsch, Varella-Garcia, Bunn, Di Maria, Veve, Bremmes, Barón, Zeng, Franklin: "Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 21, Issue 20, pp. 3798-807, (2003) (PubMed).
抗原

EGFR (Epidermal Growth Factor Receptor (EGFR))

别名

EGFR

背景

The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

分子量

134277

NCBI登录号

NP_005219, NP_958439, NP_958440, NP_958441

UniProt

P00533

途径

NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins