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EGFR 抗体 (AA 1070-1099)

Name: EGFR 抗体 (AA 1070-1099)
SKU: ABIN1881287
Availability: OutOfStock

EGFR 适用: 人 WB 宿主: 兔 Polyclonal RB11265 unconjugated

EGFR Antibody (p) p western blot analysis in A431,Hela,HUVEC,PC-3 cell line lysates (35 μg/lane). (EGFR 抗体 (AA 1070-1099))

1 image

(7 references)

产品编号 ABIN1881287

发货至: 中国

Datasheet as PDF

抗原 See all EGFR 抗体

EGFR (Epidermal Growth Factor Receptor (EGFR))
抗原表位
39

38

31

31

30

27

27

26

24

22

19

18

16

16

16

15

15

15

11

11

10

9

9

9

8

8

7

6

5

5

5

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3
AA 1070-1099
适用
749

296

283

25

25

24

19

14

8

3

2

2

1

1

1

1

1

1
人
宿主
579

167

14

13

5

4

1

1
兔
Compatible Secondaries
克隆类型
541

238

2
多克隆
标记
411

58

29

22

19

17

16

16

16

16

16

11

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

1

1

1

1

1

1
This EGFR antibody is un-conjugated
应用范围
534

250

149

147

126

102

98

93

82

46

37

34

34

18

11

8

6

5

4

4

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1070-1099 amino acids from human EGFR.

克隆位点

RB11265

亚型

Ig Fraction

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anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
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anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR 适用: 人, 小鼠, 大鼠, Pig, 猴, Cow, 小鸡, 犬, 马, 兔, 豚鼠, Avian, Cat, 驴, 山羊, Hamster, 绵羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibody
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anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibody
EGFR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5E10D3 unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR 适用: 人, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibody
EGFR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Dong, Zhang, Sun, Liu, Yin, Li, Zheng, Zeng: "Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stress." in: Scientific reports, Vol. 6, pp. 36860, (2018) (PubMed).

Luo, Zhao, Shi, Feng, Chen, Li: "Induction of Apoptosis in Human Leukemic Cell Lines by Diallyl Disulfide via Modulation of EGFR/ERK/PKM2 Signaling Pathways." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 16, Issue 8, pp. 3509-15, (2015) (PubMed).

Zanardi, Yei, Lichtenstein, Tollefson, Wold: "Distinct domains in the adenovirus E3 RIDalpha protein are required for degradation of Fas and the epidermal growth factor receptor." in: Journal of virology, Vol. 77, Issue 21, pp. 11685-96, (2003) (PubMed).

Krug, Grossmann, Schuster, Freudinger, Mildenberger, Govindan, Gekle: "Aldosterone stimulates epidermal growth factor receptor expression." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 43060-6, (2003) (PubMed).

Huang, Jiang, Sorkin: "Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking." in: The Journal of biological chemistry, Vol. 278, Issue 44, pp. 43411-7, (2003) (PubMed).

He, Huang, Gentry, Chignell: "Epidermal growth factor receptor down-regulation induced by UVA in human keratinocytes does not require the receptor kinase activity." in: The Journal of biological chemistry, Vol. 278, Issue 43, pp. 42457-65, (2003) (PubMed).

Hirsch, Varella-Garcia, Bunn, Di Maria, Veve, Bremmes, Barón, Zeng, Franklin: "Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 21, Issue 20, pp. 3798-807, (2003) (PubMed).
抗原

EGFR (Epidermal Growth Factor Receptor (EGFR))

别名

EGFR (EGFR 产品)

背景

The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

分子量

134277

NCBI登录号

NP_005219, NP_958439, NP_958440, NP_958441

UniProt

P00533

途径

NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins