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CDK2 抗体 (AA 1-30)

Name: CDK2 抗体 (AA 1-30)
SKU: ABIN1881192
Availability: OutOfStock

Cited in 5+ publications. This anti-CDK2 antibody is a 兔多克隆 antibody detecting CDK2 in WB 和 IHC (p). Suitable for 人.

Cdk2 Antibody (T14) (ABIN1881192 and ABIN2841623) western blot analysis in 293,Hela cell line lysates (35 μg/lane). (CDK2 抗体 (AA 1-30))

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CDK2 Antibody (T14) (ABIN1881192 and ABIN2841623) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (CDK2 抗体 (AA 1-30))

IHC (p)

2 images

(5 references)

产品编号 ABIN1881192

发货至: 中国

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Quick Overview for CDK2 抗体 (AA 1-30) (ABIN1881192)

抗原

See all CDK2 抗体

CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CDK2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB7918

Discover our top product CDK2 Primary Antibody

抗原表位
29

28

24

16

15

14

9

8

8

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-30

预测反应

B, Ha, M, Rat, X

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This CDK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human CDK2.

亚型

Ig Fraction
anti-Cyclin-Dependent Kinase 2 (CDK2) antibody
CDK2 适用: 人, 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1A6 unconjugated

anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 197-295) antibody
CDK2 适用: 人, 小鼠 WB, IHC, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 1A6 unconjugated

anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 211-298) antibody
CDK2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2E8 unconjugated

anti-Cyclin-Dependent Kinase 2 (CDK2) antibody
CDK2 适用: 人, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 4B4 unconjugated

anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 1-298) antibody
CDK2 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 2 (CDK2) antibody
KD Validated CDK2 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2295 unconjugated Recombinant Antibody

anti-Cyclin-Dependent Kinase 2 (CDK2) antibody
KD Validated CDK2 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB4315 unconjugated Recombinant Antibody

anti-Cyclin-Dependent Kinase 2 (CDK2) antibody
CDK2 适用: 人, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 1C4 unconjugated

anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 81-298) antibody
CDK2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 2 (CDK2) (AA 94-198) antibody
CDK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Moshinsky, Bellamacina, Boisvert, Huang, Hui, Jancarik, Kim, Rice: "SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2." in: Biochemical and biophysical research communications, Vol. 310, Issue 3, pp. 1026-31, (2003) (PubMed).

Chow, Siu, Ho, Ma, Ho, Poon: "Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints." in: The Journal of biological chemistry, Vol. 278, Issue 42, pp. 40815-28, (2003) (PubMed).

ONions, Allday: "Epstein-Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2." in: Oncogene, Vol. 22, Issue 46, pp. 7181-91, (2003) (PubMed).

Yun, Chae, Choi, Kim, Bang, Chung, Choi, Mantovani, Shin: "Cdk2-dependent phosphorylation of the NF-Y transcription factor and its involvement in the p53-p21 signaling pathway." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36966-72, (2003) (PubMed).

Izumiya, Lin, Ellison, Levy, Mayeur, Izumiya, Kung: "Cell cycle regulation by Kaposi's sarcoma-associated herpesvirus K-bZIP: direct interaction with cyclin-CDK2 and induction of G1 growth arrest." in: Journal of virology, Vol. 77, Issue 17, pp. 9652-61, (2003) (PubMed).
抗原

CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

别名

CDK2

背景

CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.

分子量

33930

NCBI登录号

NP_001789, NP_439892

UniProt

P24941

途径

PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA