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CCR5 抗体 (AA 151-177)

Name: CCR5 抗体 (AA 151-177)
SKU: ABIN1881182
Availability: OutOfStock

This anti-CCR5 antibody is a 兔多克隆 antibody detecting CCR5 in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.

CCR5 Antibody (Center) (ABIN1881182 and ABIN2838678) western blot analysis in MDA-M cell line lysates (35 μg/lane). (CCR5 抗体 (AA 151-177))

1 image

(4 references)

产品编号 ABIN1881182

发货至: 中国

Datasheet as PDF

Quick Overview for CCR5 抗体 (AA 151-177) (ABIN1881182)

抗原

See all CCR5 抗体

CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CCR5 antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB41438

Discover our top product CCR5 Primary Antibody

抗原表位
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9

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5

5

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3

2

2

2

2

1

1

1

1

1

1

1

1

1

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1

1

1

1

1

1

1

1

1

1

1
AA 151-177

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This CCR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the Central region of human CCR5.

亚型

Ig Fraction
anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人 IHC (fro) 宿主: 小鼠 Monoclonal 12D1 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) antibody
CCR5 适用: 人, 大鼠 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6G11D1 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 19-34), (N-Term) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 201-300) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 151-200) antibody
CCR5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibody
CCR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-352) antibody
CCR5 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 1-22) antibody
CCR5 适用: 人 WB, ELISA, FACS, IP, ICC 宿主: 小鼠 Monoclonal T21-8 unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (pSer336) antibody
CCR5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Receptor 5 (CCR5) (AA 100-200) antibody
CCR5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Gérard, Stanich, Oszust, Whittum-Hudson, Carter, Schumacher, Hudson: "Functional CCR5 receptor protects patients with arthritis from high synovial burden of infecting Chlamydia trachomatis." in: The American journal of the medical sciences, Vol. 340, Issue 6, pp. 448-51, (2010) (PubMed).

Hammad, Kuang, Yan, Allen, Dupré: "Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34653-64, (2010) (PubMed).

Martens, Gross, van der Steege, Brouwer, Berden, de Sevaux, Derksen, Voskuyl, Berger, Navis, Kallenberg, Bijl: "Lack of association of C-C chemokine receptor 5 Δ32 deletion status with rheumatoid arthritis, systemic lupus erythematosus, lupus nephritis, and disease severity." in: The Journal of rheumatology, Vol. 37, Issue 11, pp. 2226-31, (2010) (PubMed).

Weng, Chien, Lin, Chung, Zavras, Tsai, Chen, Yang: "Effect of CC chemokine ligand 5 and CC chemokine receptor 5 genes polymorphisms on the risk and clinicopathological development of oral cancer." in: Oral oncology, Vol. 46, Issue 10, pp. 767-72, (2010) (PubMed).
抗原

CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

别名

CCR5

背景

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

分子量

40524

NCBI登录号

NP_000570, NP_001093638

UniProt

P51681

途径

Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size