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Cyclin B2 抗体 (pSer22)

Cited in 5+ publications. This anti-Cyclin B2 antibody is a 兔 多克隆 antibody detecting Cyclin B2 in DB. Suitable for 人.
产品编号 ABIN1881157
发货至: 中国
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Room 801-803
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Quick Overview for Cyclin B2 抗体 (pSer22) (ABIN1881157)

抗原

See all Cyclin B2 (CCNB2) 抗体
Cyclin B2 (CCNB2)

适用

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宿主

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克隆类型

  • 95
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多克隆

标记

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This Cyclin B2 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB42147
  • 抗原表位

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    pSer22

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CCNB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S22 of human CCNB2.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Haraguchi, Ishikawa, Yamaguchi, Fujisawa: "Cyclin and protamine as prognostic molecular marker for testicular sperm extraction in patients with azoospermia." in: Fertility and sterility, Vol. 91, Issue 4 Suppl, pp. 1424-6, (2009) (PubMed).

    De Martino, Visone, Wierinckx, Palmieri, Ferraro, Cappabianca, Chiappetta, Forzati, Lombardi, Colao, Trouillas, Fedele, Fusco: "HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas." in: Cancer research, Vol. 69, Issue 5, pp. 1844-50, (2009) (PubMed).

    Cunningham, Vierkant, Sellers, Phelan, Rider, Liebow, Schildkraut, Berchuck, Couch, Wang, Fridley, Gentry-Maharaj, Menon, Hogdall, Kjaer, Whittemore, DiCioccio, Song, Gayther, Ramus, Pharaoh, Goode: "Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis." in: British journal of cancer, Vol. 101, Issue 8, pp. 1461-8, (2009) (PubMed).

    Bellanger, de Gramont, Sobczak-Thépot: "Cyclin B2 suppresses mitotic failure and DNA re-replication in human somatic cells knocked down for both cyclins B1 and B2." in: Oncogene, Vol. 26, Issue 51, pp. 7175-84, (2007) (PubMed).

    Stav, Bar, Sandbank: "Usefulness of CDK5RAP3, CCNB2, and RAGE genes for the diagnosis of lung adenocarcinoma." in: The International journal of biological markers, Vol. 22, Issue 2, pp. 108-13, (2007) (PubMed).

  • 抗原

    Cyclin B2 (CCNB2)

    别名

    CCNB2

    背景

    Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

    分子量

    45282

    NCBI登录号

    NP_004692

    UniProt

    O95067

    途径

    Cell Division Cycle, M Phase
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