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Cyclin B2 抗体

CCNB2 适用: 人, 小鼠, 大鼠, 非洲爪蟾 ELISA, IHC, Coat 宿主: 小鼠 Monoclonal X29-2 unconjugated
产品编号 ABIN6941010
发货至: 中国
  • 抗原 See all Cyclin B2 (CCNB2) 抗体
    Cyclin B2 (CCNB2)
    适用
    • 87
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    人, 小鼠, 大鼠, 非洲爪蟾
    宿主
    • 97
    • 4
    • 3
    小鼠
    克隆类型
    • 89
    • 15
    单克隆
    标记
    • 44
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    This Cyclin B2 antibody is un-conjugated
    应用范围
    • 55
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    • 43
    • 14
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    ELISA, Immunohistochemistry (IHC), Coating (Coat)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant full-length Xenopus laevis Cyclin B2 protein
    克隆位点
    X29-2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CCNB2 Primary Antibody
  • 应用备注

    Positive Control: HeLa cells. Human cervical tissue (IHC).

    Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Cyclin B2 (CCNB2)
    别名
    CCNB2 (CCNB2 产品)
    别名
    HsT17299 antibody, CycB2 antibody, sb:cb303 antibody, cycB2 antibody, LOC100136691 antibody, C-B2 antibody, cyclinb2 antibody, hst17299 antibody, LOC100282653 antibody, cyclin B2 antibody, cyclin B2 S homeolog antibody, CCNB2 antibody, Ccnb2 antibody, ccnb2 antibody, LOC100136691 antibody, LOC100282653 antibody, ccnb2.S antibody
    背景
    In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1). The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.
    分子量
    51kDa
    基因ID
    9133
    UniProt
    O95067
    途径
    Cell Division Cycle, M Phase
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