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ASCL1 抗体 (N-Term)

Cited in 5+ publications. This 兔 多克隆 anti-ASCL1 antibody (Clone RB41522) specifically detects ASCL1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881074
发货至: 中国
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Quick Overview for ASCL1 抗体 (N-Term) (ABIN1881074)

抗原

See all ASCL1 抗体
ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ASCL1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41522
  • 抗原表位

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    AA 63-90, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ASCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human ASCL1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Phi, Kim, Eun, Wang, Park, Choi, Kim, Park, Cho, Kim: "Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas." in: Journal of neurosurgery. Pediatrics, Vol. 5, Issue 6, pp. 608-14, (2010) (PubMed).

    McGaughey, McCallion: "Efficient discovery of ASCL1 regulatory sequences through transgene pooling." in: Genomics, Vol. 95, Issue 6, pp. 363-9, (2010) (PubMed).

    Li, Zhong, Li, Huang, Wang, Zheng, Zhang: "[Expression and clinicopathologic significance of human achaete-scute homolog 1 in pulmonary neuroendocrine tumors]." in: Zhongguo fei ai za zhi = Chinese journal of lung cancer, Vol. 13, Issue 4, pp. 317-21, (2010) (PubMed).

    Deng, Yang, Le, Deng, Xu, Xiong, Zhu, Xie, Song, Jankovic: "Examination of the MASH1 gene in patients with Parkinson's disease." in: Biochemical and biophysical research communications, Vol. 392, Issue 4, pp. 548-50, (2010) (PubMed).

    Improgo, Schlichting, Cortes, Zhao-Shea, Tapper, Gardner: "ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus." in: Molecular cancer research : MCR, Vol. 8, Issue 2, pp. 194-203, (2010) (PubMed).

  • 抗原

    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

    别名

    ASCL1

    背景

    This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

    分子量

    25454

    NCBI登录号

    NP_004307

    UniProt

    P50553

    途径

    Dopaminergic Neurogenesis
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