LPAR3 抗体 (C-Term)
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Quick Overview for LPAR3 抗体 (C-Term) (ABIN187789)
抗原
See all LPAR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with EDG-7. Species Reactivity: Human, other species not tested.
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过滤
- 0.2 μm filtered
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免疫原
- Synthetic peptide derived from the C-terminal of the EDG-7 receptor.
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应用备注
- Western Blot: Use at 5-10 µg/ml using a human EDG-7 receptor transfected cell line. The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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缓冲液
- Rabbit polyclonal antibody against human EDG-7 (CT). Available at 100 µg/100 µl in PBS with 0.08% sodium azide. Purification: Sterile filtered at 0.2 µm.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))
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别名
- EDG-7 / LPAR3
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背景
- EDG-7 belongs to a family of G-protein coupled receptors whose lignads are lysophospholipids. The ligand for EDG-7 sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-7 is expressed in prostate as well as other tissues.
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途径
- Regulation of Cell Size
抗原
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