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Caspase 2 抗体

CASP2 适用: 人, 小鼠, 大鼠, 犬 WB, IP 宿主: 大鼠 Monoclonal 11B4 unconjugated
产品编号 ABIN187544
发货至: 中国
  • 抗原 See all Caspase 2 (CASP2) 抗体
    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
    适用
    • 99
    • 38
    • 25
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 91
    • 6
    • 4
    大鼠
    克隆类型
    • 80
    • 21
    单克隆
    标记
    • 59
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caspase 2 antibody is un-conjugated
    应用范围
    • 73
    • 34
    • 23
    • 14
    • 14
    • 14
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    Recognizes an epitope in the p19 subunit of human, mouse, rat, monkey and dog caspase-2. Detects bands of ~51 kDa (procaspase-2), ~32 kDa and ~18 kDa (cleavage products) by Western blot. Species Reactivity: Human, mouse, rat, monkey and dog. Others not tested.
    免疫原
    p19 fragment of recombinant human Caspase-2.
    克隆位点
    11B4
    亚型
    IgG2a
    Top Product
    Discover our top product CASP2 Primary Antibody
  • 应用备注
    Immunoprecipitation Western blot: Use at 2 µg/mL. The optimal dilution for a specific application should be determined by the researcher. Figure (left column): Detection of procaspase-2 (p51), an intermediate cleavage product of caspase-2 (p32) and activated caspase-2 (p19) in FDC-P1 cells (mouse IL-3 dependent promyelocytic line) during growth factor withdrawal induced apoptosis. Activation of caspase-2 is inhibited in the presence of the caspase inhibitor Z-VAD-FMK (AB-001). Figures (above): Western blot analysis of cell lysates from human and mouse cell lines with clone 11B4 (MC-498). Clone 11B4 demonstrates its ability to recognize an approximately 51 kDa protein that corresponds to endogenous procaspase-2. Hsp-70 was used as an equal loading control, and -/- caspase-2 cells were used as a negative control.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 µL of protein G affinity-purified monoclonal antibody at 1 mg/mL in PBS containing 0.02% sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
    别名
    Caspase-2 (CASP2 产品)
    别名
    xCaspase-2 antibody, Caspase-2 antibody, ICH-1 antibody, Nedd2 antibody, CASP-2 antibody, ICH1 antibody, NEDD-2 antibody, NEDD2 antibody, PPP1R57 antibody, ICH-1L/1S antibody, ICH1L1S antibody, caspase 2 antibody, caspase 2 L homeolog antibody, caspase-2 antibody, CASP2 antibody, casp2.L antibody, CpipJ_CPIJ008254 antibody, Casp2 antibody
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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