XRCC6 抗体
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北京 101111
Quick Overview for XRCC6 抗体 (ABIN187448)
抗原
See all XRCC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts with the p70 Ku antigen subunit. Recognizes an epitope between aa 506-541 of p70. Species Reactivity: Human, monkey and Xenopus. Mouse and hamster (Western blots only). Does not react with bovine, rabbit or sea urchin. Other species not tested. Cellular Location: Nuclear.Positive Control: BT474, T47D, HEP-G-2 or HeLa cells. Tonsil.
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免疫原
- Human placental extract designated as PSE1-PL.
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亚型
- IgG2b
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (C-Term) antibody
XRCC6 适用: 人 WB, IF, ICC, IHC (p), IP, PLA 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 1-609) antibodyXRCC6 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C2-1A6 unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 397-603) antibodyXRCC6 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 319-538) antibodyXRCC6 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 408-609) antibodyXRCC6 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 6-214) antibodyXRCC6 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2F7F5 unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (acLys542) antibodyXRCC6 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) antibodyXRCC6 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (C-Term) antibodyXRCC6 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (AA 521-548), (C-Term) antibodyXRCC6 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20806 unconjugated
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应用备注
- Immunofluorescence Immunohistochemistry: (Formalin/paraffin) Use at a 1:400 dilution for 30 minutes at room temperature (RT). Staining of formalin-fixed tissues is improved by boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min. followed by cooling to RT for 20 min. Immunoprecipitation: (Native and denatured) Use at 2 µg/mg protein lysate. Use Protein A. Western blot: Use at 0.25-0.5 µg/mL for 2 hrs. at RT. The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 µg of monoclonal antibody at 200 µg/mL in 10 mM PBS, pH 7.4, with protein stabilizer and 0.09% sodium azide. Purified from ascites fluid by Protein A chromatography.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
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别名
- XRCC6 / Ku70
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背景
- The Ku autoantigen is a heterodimer of 70 kDa (p70) and ~80 kDa (p80) proteins. The p70/p80 dimer is important for the function of a 460 kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53 and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation and apoptosis.
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途径
- DNA Damage Repair
抗原
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