JUP 抗体
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北京 101111
Quick Overview for JUP 抗体 (ABIN187369)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts with human plakoglobin. Cross-reacts with rat and weakly cross-reacts with mouse plakoglobin. Species Reactivity: Human, mouse and rat. Others not tested.
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过滤
- 0.2 μm filtered
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亚型
- IgG1
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anti-Junction Plakoglobin (JUP) antibody
JUP 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-745) antibodyJUP 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Junction Plakoglobin (JUP) (C-Term) antibodyVerified JUP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) (AA 556-745) antibodyJUP 适用: 人, 小鼠, 大鼠 WB, IF, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠, 大鼠, 小鸡, 犬, Cow, Cat WB, IF, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 15F11 unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal [11E4] unconjugated
anti-Junction Plakoglobin (JUP) (AA 1-300) antibodyJUP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Junction Plakoglobin (JUP) antibodyJUP 适用: 人 WB, IF, IHC, FACS 宿主: 小鼠 Monoclonal CTNG-1664 unconjugated
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应用备注
- Immunofluorescence: (cells fixed in paraformaldehyde) Use at a 1:10 dilution Immunoprecipitation Western blot: Use at a 1:10 dilution The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1 mL at 100 µg/mL of 0.2 µm filtered antibody solution in PBS containing 0.1% protein stabilizer.
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储存条件
- 4 °C
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- JUP (Junction Plakoglobin (JUP))
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别名
- Junction plakoglobin
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背景
- Plakoglobin belongs together with alpha- and beta-catenin to the catenin family. Catenins mediate cell-cell adhesion by interaction with cadherins. Plakoglobin is found in desmosomes and adherens junctions. Plakoglobin is highly homologous to beta-catenin although its function differs from that of beta-catenin. Whereas beta-catenin has been found in potentiating hyperproliferation and tumor formation, plakoglobin can suppress tumorigenicity. Overexpression of plakoglobin has been shown to suppress cell proliferation and cell tumorigenicity in animals. Furthermore reduced plakoblobin expression has been found in tumor tissues and metastatic lesions of renal cells, esophageal carcinomas and in skin carcinomas.
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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