PGRMC1 抗体 (C-Term)
Quick Overview for PGRMC1 抗体 (C-Term) (ABIN185610)
抗原
See all PGRMC1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- PGRMC1 / MPR
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序列
- EPKDESARKN D
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-EPKDESARKND, from the C Terminus of the protein sequence according to NP_006658.1.
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亚型
- IgG
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应用备注
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Immunohistochemistry: Paraffin embedded Human Testis. Recommended concentration: 5 μg/mL.
Western Blot: Approx 24 kDa band observed in Human Kidney, Liver and Testis lysates, and approx 25 kDa in Mouse Testis lysates (calculated MW of 21.7 kDa according to Human NP_006658.1 and Mouse NP_058063.2). These molecular weights are routinely observed b
Peptide ELISA: antibody detection limit dilution 1:4000.
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说明
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Immunofluorescence: This antibody has been successfully used in IF on Human: Izzo, N. J et al. (2014) PMID: 25390692.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity." in: PLoS ONE, Vol. 9, Issue 11, pp. e111899, (2015) (PubMed).
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: "Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity." in: PLoS ONE, Vol. 9, Issue 11, pp. e111899, (2015) (PubMed).
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- PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
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别名
- PGRMC1
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背景
- PGRMC1, MPR, progesterone receptor membrane component 1 , HGNC:16090, HPR6.6, progesterone binding protein
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基因ID
- 10857, 53328
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NCBI登录号
- NP_006658
抗原
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