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PGRMC1 抗体 (C-Term)

Cited in 1 publication. This anti-PGRMC1 antibody is a 山羊 多克隆 antibody detecting PGRMC1 in WB, IHC, ELISA 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN185610
发货至: 中国
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Quick Overview for PGRMC1 抗体 (C-Term) (ABIN185610)

抗原

See all PGRMC1 抗体
PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))

适用

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人, 小鼠

宿主

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山羊

克隆类型

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多克隆

标记

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This PGRMC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

质量等级

Verified
  • 抗原表位

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    C-Term

    原理

    PGRMC1 / MPR

    序列

    EPKDESARKN D

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence C-EPKDESARKND, from the C Terminus of the protein sequence according to NP_006658.1.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: Paraffin embedded Human Testis. Recommended concentration: 5 μg/mL.

    Western Blot: Approx 24 kDa band observed in Human Kidney, Liver and Testis lysates, and approx 25 kDa in Mouse Testis lysates (calculated MW of 21.7 kDa according to Human NP_006658.1 and Mouse NP_058063.2). These molecular weights are routinely observed b

    Peptide ELISA: antibody detection limit dilution 1:4000.

    说明

    Immunofluorescence: This antibody has been successfully used in IF on Human: Izzo, N. J et al. (2014) PMID: 25390692.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Minimize freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Izzo, Xu, Zeng, Kirk, Mozzoni, Silky, Rehak, Yurko, Look, Rishton, Safferstein, Cruchaga, Goate, Cahill, Arancio, Mach, Craven, Head, LeVine, Spires-Jones, Catalano: "Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity." in: PLoS ONE, Vol. 9, Issue 11, pp. e111899, (2015) (PubMed).

  • 抗原

    PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))

    别名

    PGRMC1

    背景

    PGRMC1, MPR, progesterone receptor membrane component 1 , HGNC:16090, HPR6.6, progesterone binding protein

    基因ID

    10857, 53328

    NCBI登录号

    NP_006658
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