PGRMC1 抗体 (Middle Region)
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北京 101111
Quick Overview for PGRMC1 抗体 (Middle Region) (ABIN3043899)
抗原
See all PGRMC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 67-102, Middle Region
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原理
- Anti-PGRMC1 Antibody
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序列
- RLKRRDFTPA ELRRFDGVQD PRILMAINGK VFDVTK
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PGRMC1 Antibody (ABIN3043899). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PGRMC1, identical to the related mouse sequence, and different from the related rat sequence by two amino acids.
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亚型
- IgG
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anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 44-195) antibody
PGRMC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibodyVerified PGRMC1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 1-195) antibodyPGRMC1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G11G8 unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibodyPGRMC1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 96-195) antibodyPGRMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibodyPGRMC1 适用: 人, Cow, 犬, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibodyPGRMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibodyPGRMC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibodyPGRMC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
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别名
- PGRMC1
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背景
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Synonyms: Membrane-associated progesterone receptor component 1,mPR,PGRMC1,HPR6.6, PGRMC,
Tissue Specificity: Widely expressed, with highest expression in liver and kidney.
Background: Progesterone receptor membrane component 1 (PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as potentially being the same as PGRMC1. The sole biochemical function of PGRMC1 is heme-binding. PGRMC1 shares key structural motifs with cytochrome b5. It binds and activates P450 proteins, which are important in drug, hormone and lipid metabolism. Also, PGRMC1 binds to PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1). However, its expression outside of the reproductive tract and in males suggests multiple functions for the protein. These may include binding to Insig (insulin-induced gene), which regulates cholesterol synthesis.
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分子量
- 26 kDa
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基因ID
- 10857
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UniProt
- O00264
抗原
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