PGRMC1 抗体 (Middle Region)
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- 抗原 See all PGRMC1 抗体
- PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
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抗原表位
- AA 67-102, Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PGRMC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Membrane-associated progesterone receptor component 1(PGRMC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- RLKRRDFTPA ELRRFDGVQD PRILMAINGK VFDVTK
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Membrane-associated progesterone receptor component 1(PGRMC1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: progesterone receptor membrane component 1
Protein Name: Membrane-associated progesterone receptor component 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PGRMC1 (67-102aa RLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTK), identical to the related mouse sequence, and different from the related rat sequence by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PGRMC1 Primary Antibody
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anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibody
Verified PGRMC1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 44-195) antibodyPGRMC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 1-195) antibodyPGRMC1 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7G11G8 unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibodyPGRMC1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (AA 96-195) antibodyPGRMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibodyPGRMC1 适用: 人, Cow, 犬, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibodyPGRMC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (C-Term) antibodyPGRMC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
- 别名
- PGRMC1 (PGRMC1 产品)
- 别名
- MGC89150 antibody, wu:fa94d03 antibody, zgc:103577 antibody, DKFZp469D0815 antibody, HPR6.6 antibody, MPR antibody, AA415812 antibody, PPMR antibody, Vema antibody, 25-Dx antibody, 25Dx antibody, VEMA antibody, progesterone receptor membrane component 1 antibody, pgrmc1 antibody, PGRMC1 antibody, Pgrmc1 antibody
- 背景
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Progesterone receptor membrane component 1 (PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene. The Sigma-2 receptor was recently identified as potentially being the same as PGRMC1. The sole biochemical function of PGRMC1 is heme-binding. PGRMC1 shares key structural motifs with cytochrome b5. It binds and activates P450 proteins, which are important in drug, hormone and lipid metabolism. Also, PGRMC1 binds to PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1). However, its expression outside of the reproductive tract and in males suggests multiple functions for the protein. These may include binding to Insig (insulin-induced gene), which regulates cholesterol synthesis.
Synonyms: HPR6.6 antibody|Membrane associated progesterone receptor component 1 antibody|Membrane-associated progesterone receptor component 1 antibody|mPR antibody|PGRC1_HUMAN antibody|PGRMC antibody|Pgrmc1 antibody|Progesterone binding protein antibody|Progesterone receptor membrane component 1 antibody - 基因ID
- 10857
- UniProt
- O00264
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