ADRB1 抗体 (Internal Region)
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北京 101111
Quick Overview for ADRB1 抗体 (Internal Region) (ABIN185584)
抗原
See all ADRB1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Internal Region
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原理
- ADRB1
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序列
- ESDEARRCYN DPK
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交叉反应
- 犬, 人, 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence ESDEARRCYNDPK, from the internal region of the protein sequence according to NP_000675.1.
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亚型
- IgG
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anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody
ADRB1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (Middle Region) antibodyADRB1 适用: 人, 大鼠, 小鼠, 犬, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 401-477) antibodyADRB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 150-250) antibodyADRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) antibodyADRB1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 200-214), (Extracellular) antibodyADRB1 适用: 大鼠 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (FITC)ADRB1 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 180-229) antibodyADRB1 适用: 人, 大鼠, 小鼠, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 200-214), (Extracellular) antibody (FITC)KO Validated ADRB1 适用: 大鼠 FACS, LCI 宿主: 兔 Polyclonal FITC
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应用备注
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Immunohistochemistry: Paraffin embedded Human Heart. Recommended concentration: 6 μg/mL.
Western Blot: This antibody is not recommended for use in Western blotting.
Peptide ELISA: antibody detection limit dilution 1:2000.
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说明
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Immunofluorescence: Strong expression of the protein seen in the plama membrane and cytoplasm of HeLa cells. Recommended concentration: 10μg/ml.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "Difference between beta1-adrenoceptor autoantibodies of human and animal origin-Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192615, (2018) (PubMed).
: "Functional autoantibodies in patients with different forms of dementia." in: PLoS ONE, Vol. 13, Issue 3, pp. e0192778, (2018) (PubMed).
: "Performance and in-house validation of a bioassay for the determination of beta1-autoantibodies found in patients with cardiomyopathy." in: Heliyon, Vol. 3, Issue 7, pp. e00362, (2017) (PubMed).
: "The first aptamer-apheresis column specifically for clearing blood of ?1-receptor autoantibodies." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 76, Issue 10, pp. 2449-55, (2012) (PubMed).
: "Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies." in: Circulation research, Vol. 109, Issue 9, pp. 986-92, (2011) (PubMed).
: "Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients." in: Journal of the American College of Cardiology, Vol. 55, Issue 5, pp. 463-8, (2010) (PubMed).
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: "Difference between beta1-adrenoceptor autoantibodies of human and animal origin-Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192615, (2018) (PubMed).
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- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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别名
- ADRB1
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背景
- ADRB1, adrenergic, beta-1-, receptor, ADRB1R, B1AR, BETA1AR, RHR, beta-1-adrenergic receptor
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分子量
- 51.2kDa
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基因ID
- 153
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NCBI登录号
- NP_000675
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途径
- cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
抗原
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