我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

ADRB1 抗体 (Internal Region)

Name: ADRB1 抗体 (Internal Region)
Brand: antibodies-online
SKU: ABIN185584
Availability: OutOfStock

This anti-ADRB1 antibody is a 山羊多克隆 antibody detecting ADRB1 in ELISA, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 6+ publications.

ABIN185584 Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0. (ADRB1 抗体 (Internal Region))

(ABIN185584) Negative Control showing staining of paraffin embedded Human Heart, with no primary antibody. (ADRB1 抗体 (Internal Region))

IHC

ABIN185584 (0. (ADRB1 抗体 (Internal Region))

ABIN185584 (4µg/ml) staining of paraffin embedded Human Heart. (ADRB1 抗体 (Internal Region))

IHC

(ABIN185584) (6 μg/mL) staining of paraffin embedded Human Heart. (ADRB1 抗体 (Internal Region))

IHC

10 images

(6 references)

产品编号 ABIN185584

发货至: 中国

Quick Overview for ADRB1 抗体 (Internal Region) (ABIN185584)

抗原

See all ADRB1 抗体

ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

适用

人

宿主

山羊

克隆类型

多克隆

标记

This ADRB1 antibody is un-conjugated

应用范围

ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

质量等级

Verified

抗原表位
16

7

4

4

3

3

1

1

1

1

1

1
Internal Region

原理

ADRB1

序列

ESDEARRCYN DPK

交叉反应

犬, 人, 小鼠, 大鼠

纯化方法

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

免疫原

Peptide with sequence ESDEARRCYNDPK, from the internal region of the protein sequence according to NP_000675.1.

亚型

IgG
anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody
ADRB1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (Middle Region) antibody
ADRB1 适用: 人, 大鼠, 小鼠, 犬, Pig, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 401-477) antibody
ADRB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 150-250) antibody
ADRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) antibody
ADRB1 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 200-214), (Extracellular) antibody
ADRB1 适用: 大鼠 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (Cy5)
ADRB1 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (FITC)
ADRB1 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 180-229) antibody
ADRB1 适用: 人, 大鼠, 小鼠, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Adrenergic, beta-1-, Receptor (ADRB1) (AA 181-250) antibody (Biotin)
ADRB1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin

应用备注

Immunohistochemistry: Paraffin embedded Human Heart. Recommended concentration: 6 μg/mL.
Western Blot: This antibody is not recommended for use in Western blotting.
Peptide ELISA: antibody detection limit dilution 1:2000.

说明

Immunofluorescence: Strong expression of the protein seen in the plama membrane and cytoplasm of HeLa cells. Recommended concentration: 10μg/ml.

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Minimize freezing and thawing.

储存条件

-20 °C

储存方法

Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
Wenzel, Schulze-Rothe, Müller, Wallukat, Haberland: "Difference between beta1-adrenoceptor autoantibodies of human and animal origin-Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192615, (2018) (PubMed).

Wallukat, Prüss, Müller, Schimke: "Functional autoantibodies in patients with different forms of dementia." in: PLoS ONE, Vol. 13, Issue 3, pp. e0192778, (2018) (PubMed).

Wenzel, Schulze-Rothe, Haberland, Müller, Wallukat, Davideit: "Performance and in-house validation of a bioassay for the determination of beta1-autoantibodies found in patients with cardiomyopathy." in: Heliyon, Vol. 3, Issue 7, pp. e00362, (2017) (PubMed).

Wallukat, Haberland, Berg, Schulz, Freyse, Dahmen, Kage, Dandel, Vetter, Salzsieder, Kreutz, Schimke: "The first aptamer-apheresis column specifically for clearing blood of ?1-receptor autoantibodies." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 76, Issue 10, pp. 2449-55, (2012) (PubMed).

Haberland, Wallukat, Dahmen, Kage, Schimke: "Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies." in: Circulation research, Vol. 109, Issue 9, pp. 986-92, (2011) (PubMed).

Wallukat, Muñoz Saravia, Haberland, Bartel, Araujo, Valda, Duchen, Diaz Ramirez, Borges, Schimke: "Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients." in: Journal of the American College of Cardiology, Vol. 55, Issue 5, pp. 463-8, (2010) (PubMed).
抗原

ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

别名

ADRB1

背景

ADRB1, adrenergic, beta-1-, receptor, ADRB1R, B1AR, BETA1AR, RHR, beta-1-adrenergic receptor

分子量

51.2kDa

基因ID

153

NCBI登录号

NP_000675

途径

cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation