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CCKBR 抗体 (Internal Region)

This anti-CCKBR antibody is a 山羊 多克隆 antibody detecting CCKBR in WB, ELISA 和 IHC. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN185407
发货至: 中国

Quick Overview for CCKBR 抗体 (Internal Region) (ABIN185407)

抗原

See all CCKBR 抗体
CCKBR (Cholecystokinin B Receptor (CCKBR))

适用

  • 30
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  • 1
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人, 小鼠

宿主

  • 45
  • 1
山羊

克隆类型

  • 45
  • 1
多克隆

标记

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This CCKBR antibody is un-conjugated

应用范围

  • 30
  • 13
  • 13
  • 11
  • 8
  • 8
  • 4
  • 4
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

质量等级

Verified
  • 抗原表位

    • 15
    • 5
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    Internal Region

    原理

    CCKBR

    序列

    FDGDSDSDSQ SRVRNQ

    交叉反应

    Cow, 人, 小鼠, 大鼠

    纯化方法

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence C-FDGDSDSDSQSRVRNQ, from the internal region of the protein sequence according to NP_795344.1.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: Paraffin embedded Human Pancreas. Recommended concentration: 4-6 μg/mL.

    Western Blot: Approx 48-50 kDa band observed in Mouse Pancreas lysates (calculated MW of 49.2 kDa according to Mouse NP_031653.1) Recommended concentration: 0.3-1 μg/mL. Primary incubation 1 hour at room temperature.

    Peptide ELISA: antibody detection limit dilution 1:32000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Minimize freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Quattrone, Dewaele, Wozniak, Bauters, Vanspauwen, Floris, Schöffski, Chibon, Coindre, Sciot, Debiec-Rychter: "Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis." in: The Journal of pathology, Vol. 228, Issue 4, pp. 565-74, (2014) (PubMed).

    El-Kouhen, Morisset: "Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line." in: Pancreas, Vol. 39, Issue 2, pp. 127-34, (2010) (PubMed).

    Berna, Seiz, Nast, Benten, Bläker, Koch, Lohse, Pace: "CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 38905-14, (2010) (PubMed).

    El-Kouhen, Morisset: "Cholecystokinin and Somatostatin Negatively Affect Growth of the Somatostatin-RIN-14B Cells." in: International journal of endocrinology, Vol. 2009, pp. 875167, (2009) (PubMed).

  • 抗原

    CCKBR (Cholecystokinin B Receptor (CCKBR))

    别名

    CCKBR

    背景

    CCKBR, cholecystokinin B receptor , HGNC:1571, CCK-B, GASR, CCK2 receptor, cholecystokinin-B receptor/gastrin receptor, gastrin receptor, gastrin\cholecystokinin brain receptor, CCK2R

    基因ID

    887, 12426, 25706

    NCBI登录号

    NP_795344

    途径

    Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour
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