CCKBR 抗体 (Internal Region)
Quick Overview for CCKBR 抗体 (Internal Region) (ABIN185407)
抗原
See all CCKBR 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Internal Region
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原理
- CCKBR
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序列
- FDGDSDSDSQ SRVRNQ
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交叉反应
- Cow, 人, 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-FDGDSDSDSQSRVRNQ, from the internal region of the protein sequence according to NP_795344.1.
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亚型
- IgG
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应用备注
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Immunohistochemistry: Paraffin embedded Human Pancreas. Recommended concentration: 4-6 μg/mL.
Western Blot: Approx 48-50 kDa band observed in Mouse Pancreas lysates (calculated MW of 49.2 kDa according to Mouse NP_031653.1) Recommended concentration: 0.3-1 μg/mL. Primary incubation 1 hour at room temperature.
Peptide ELISA: antibody detection limit dilution 1:32000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis." in: The Journal of pathology, Vol. 228, Issue 4, pp. 565-74, (2014) (PubMed).
: "Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line." in: Pancreas, Vol. 39, Issue 2, pp. 127-34, (2010) (PubMed).
: "CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 38905-14, (2010) (PubMed).
: "Cholecystokinin and Somatostatin Negatively Affect Growth of the Somatostatin-RIN-14B Cells." in: International journal of endocrinology, Vol. 2009, pp. 875167, (2009) (PubMed).
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Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis." in: The Journal of pathology, Vol. 228, Issue 4, pp. 565-74, (2014) (PubMed).
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- CCKBR (Cholecystokinin B Receptor (CCKBR))
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别名
- CCKBR
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背景
- CCKBR, cholecystokinin B receptor , HGNC:1571, CCK-B, GASR, CCK2 receptor, cholecystokinin-B receptor/gastrin receptor, gastrin receptor, gastrin\cholecystokinin brain receptor, CCK2R
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基因ID
- 887, 12426, 25706
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NCBI登录号
- NP_795344
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途径
- Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour
抗原
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