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CD276 抗体 (AA 1-242)

CD276 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal MJ18 unconjugated
产品编号 ABIN1820150
发货至: 中国
  • 抗原 See all CD276 抗体
    CD276
    抗原表位
    • 15
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-242
    适用
    • 64
    • 38
    • 10
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 49
    • 17
    • 9
    • 1
    大鼠
    克隆类型
    • 44
    • 31
    • 1
    单克隆
    标记
    • 42
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD276 antibody is un-conjugated
    应用范围
    • 47
    • 24
    • 23
    • 14
    • 13
    • 11
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    Flow Cytometry (FACS)
    特异性
    Recognizes mouse CD276, otherwise known as B7-H3, a ubiquitously expressed transmembrane glycoprotein and member of the B7 family of co-stimulatory molecules, which acts as both a positive and negative regulator of T-cell-mediated immune responses. CD276 is highly expressed in bone during embryogenesis, and can be induced on dendritic cells and monocytes by inflammatory cytokines. CD276 has been implicated in the development of acute and chronic transplant rejection, and is reported to have therapeutic potential as a regulator of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy. In mice, CD276 has been linked with the development of pathogenic Th2 cells during the induction phase of allergic asthma. Studies have shown that clone MJ18 inhibits stimulated CD4+ T-cell proliferation.
    纯化方法
    Protein G purified
    免疫原
    Mouse IgG2a Fc-CD276 (aa 1-242).

    Type of Immunogen: Fusion protein
    克隆位点
    MJ18
    亚型
    IgG1
    Top Product
    Discover our top product CD276 Primary Antibody
  • 应用备注
    Approved: Flo (1:25 - 1:200)
    说明

    Target Species of Antibody: Mouse

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    CD276
    别名
    CD276 / B7-H3 (CD276 产品)
    背景
    Name/Gene ID: CD276

    Synonyms: CD276, 4Ig-B7-H3, B7 homolog 3, B7-H3, CD276 antigen, CD276 Molecule, Costimulatory molecule, B7H3, B7RP-2
    基因ID
    80381
    UniProt
    Q5ZPR3
    途径
    Cancer Immune Checkpoints
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