CD31 抗体 (PE)
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北京 101111
Quick Overview for CD31 抗体 (PE) (ABIN182012)
抗原
See all CD31 (PECAM1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises PECAM-1 (CD31), a type 1 transmembrane protein expressed primarily on endothelial cells, platelets and leucocytes. Clone TLD-3A12 has been shown to partially block the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen (3). We recommend the use of SM272LE for use in Functional Studies.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Activated, Lewis rat derived microglial cells. Remarks: Spleen cells from immunised BALB/c mouse were fused with cells of the mouse SP2 myeloma cell line.
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亚型
- IgG1
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应用备注
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Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1 mL distilled water
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浓度
- 0.1 mg/mL
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缓冲液
- PBS containing 1 % BSA, 5 % Sucrose and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- This product is photosensitive and should be protected from light
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储存条件
- 4 °C
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储存方法
- Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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别名
- CD31 / PECAM1
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背景
- CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).Synonyms: End °CAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
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基因ID
- 29583
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NCBI登录号
- NP_113779
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UniProt
- Q3SWT0
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途径
- Regulation of Actin Filament Polymerization
抗原
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