LAMP2 抗体 (FITC)
Quick Overview for LAMP2 抗体 (FITC) (ABIN1819854)
抗原
See all LAMP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes canine CD107b, otherwise known as LAMP-2, a 95kD heavily-glycosylated type I integral lysosomal glycoprotein, shown to share high N-terminal amino acid sequence homology with human, mouse and rat CD107b. Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion. Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion. Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential. Clone AC17 has been shown as suitable for use in Electron Microscopy.
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无交叉反应
- 小鼠, 大鼠
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纯化方法
- Protein G purified
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免疫原
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MDCK (Madin-Darby Canine Kidney) cells.
Type of Immunogen: Cells -
亚型
- IgG1
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应用备注
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Approved: Flo (1:1), IF, IP, WB
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Dog
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide, 1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Protect from light.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
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别名
- LAMP2 / CD107b
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背景
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Name/Gene ID: LAMP2
Family: Cancer
Synonyms: LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2 -
基因ID
- 3920
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途径
- Autophagy
抗原
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