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CCR2 抗体 (AA 17-39)

This 山羊 多克隆 anti-CCR2 antibody specifically detects CCR2 in WB, ELISA, IHC 和 IHC (p). The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN1819414
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CCR2 抗体 (AA 17-39) (ABIN1819414)

抗原

See all CCR2 抗体
CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

适用

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人, 猴

宿主

  • 100
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山羊

克隆类型

  • 83
  • 39
  • 2
多克隆

标记

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This CCR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 17-39

    特异性

    Recognizes an epitope within the N-terminal (NT) region of human CD192, otherwise known as CCR2 (C-C chemokine receptor type 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4. Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1.

    纯化方法

    Affinity purified

    免疫原

    Synthetic peptide C-GEEVTTFFDYDYGAPCHKFDVKQ corresponding to amino acids 17-39 within the N-terminal region of human CD192. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Orangutan (96%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: ELISA (1:60000), IHC, IHC-P (1:200), WB (1:1000)

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 0.09 % sodium azide, 0.1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

    别名

    CCR2

    背景

    Name/Gene ID: CCR2
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CCR2, C-C chemokine receptor type 2, CD192, Cc chemokine receptor 2, CCR-2, CCR2A, C-C CKR-2, CKR2, CD192 antigen, CKR2A, CKR2B, Mcp1 receptor, MCP-1 receptor, MCP-1-R, C-c chemokine receptor 2, CC-CKR-2, Cc-ckr2, CCR2B, CMKBR2, Mcp1r

    基因ID

    729230

    途径

    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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