CCR2 抗体 (AA 17-39)
Quick Overview for CCR2 抗体 (AA 17-39) (ABIN1819414)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-39
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特异性
- Recognizes an epitope within the N-terminal (NT) region of human CD192, otherwise known as CCR2 (C-C chemokine receptor type 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4. Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1.
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纯化方法
- Affinity purified
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免疫原
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Synthetic peptide C-GEEVTTFFDYDYGAPCHKFDVKQ corresponding to amino acids 17-39 within the N-terminal region of human CD192. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Orangutan (96%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
- Approved: ELISA (1:60000), IHC, IHC-P (1:200), WB (1:1000)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide, 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
- CCR2
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背景
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Name/Gene ID: CCR2
Subfamily: Chemokine
Family: GPCR
Synonyms: CCR2, C-C chemokine receptor type 2, CD192, Cc chemokine receptor 2, CCR-2, CCR2A, C-C CKR-2, CKR2, CD192 antigen, CKR2A, CKR2B, Mcp1 receptor, MCP-1 receptor, MCP-1-R, C-c chemokine receptor 2, CC-CKR-2, Cc-ckr2, CCR2B, CMKBR2, Mcp1r -
基因ID
- 729230
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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