CCR2 抗体 (AA 17-39)
Quick Overview for CCR2 抗体 (AA 17-39) (ABIN1819414)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
- 
    
- 
                                            
抗原表位
 - AA 17-39
 - 
                                            
特异性
 - Recognizes an epitope within the N-terminal (NT) region of human CD192, otherwise known as CCR2 (C-C chemokine receptor type 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4. Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1.
 - 
                                            
纯化方法
 - Affinity purified
 - 
                                            
免疫原
 - 
                        Synthetic peptide C-GEEVTTFFDYDYGAPCHKFDVKQ corresponding to amino acids 17-39 within the N-terminal region of human CD192. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Orangutan (96%).
Type of Immunogen: Synthetic peptide - 
                                            
亚型
 - IgG
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - Approved: ELISA (1:60000), IHC, IHC-P (1:200), WB (1:1000)
 - 
                                            
说明
 - 
                        
Target Species of Antibody: Human
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Liquid
 - 
                                            
浓度
 - Lot specific
 - 
                                            
缓冲液
 - PBS, 0.09 % sodium azide, 0.1 % BSA
 - 
                                            
储存液
 - Sodium azide
 - 
                                            
注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 - 
                                            
储存条件
 - 4 °C,-20 °C
 - 
                                            
储存方法
 - 4°C or -20°C, Avoid freeze-thaw cycles.
 
 - 
                                            
 - 
    
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
 - 
                                            
别名
 - CCR2
 - 
                                            
背景
 - 
                        Name/Gene ID: CCR2
Subfamily: Chemokine
Family: GPCR
Synonyms: CCR2, C-C chemokine receptor type 2, CD192, Cc chemokine receptor 2, CCR-2, CCR2A, C-C CKR-2, CKR2, CD192 antigen, CKR2A, CKR2B, Mcp1 receptor, MCP-1 receptor, MCP-1-R, C-c chemokine receptor 2, CC-CKR-2, Cc-ckr2, CCR2B, CMKBR2, Mcp1r - 
                                            
基因ID
 - 729230
 - 
                                            
途径
 - cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
 
抗原
 -