TIMD4 抗体 (AA 1-288)
-
- 抗原 See all TIMD4 抗体
- TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
-
抗原表位
- AA 1-288
-
适用
- 小鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This TIMD4 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)
- 特异性
- Clone RMT4-54 specifically recognizes mouse Tim-4 (T-cell immunoglobulin mucin 4), a transmembrane glycoprotein and member of the immunoglobulin superfamily, exclusively expressed by antigen-presenting cells, which acts as the natural ligand of Tim-1, involved in T-cell expansion and cytokine production. Tim-4 is reported to be crucial for the phagocytosis of apoptotic cells by peritoneal macrophages, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on DCs, enhances Th2 cell function. The TIM-4 gene locus is associated with predisposition to asthma in both mice and humans and may be considered as a candidate disease gene for asthma. Studies have shown that clone RMT4-54 significantly inhibits the efficient phagocytosis of apoptotic cells by PRMs (peritoneal resident Mac1+ cells), but not PEMs (peritoneal exudate Mac1+ cells) see for details.
- 纯化方法
- Protein G purified
- 免疫原
- Tim-4-Ig, consisting of amino acids 1-288 of mouse Tim-4, coupled with the Fc portion of mouse IgG2a.
- 克隆位点
- RMT4-54
- 亚型
- IgG2a
- Top Product
- Discover our top product TIMD4 Primary Antibody
-
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 134-301) antibody
TIMD4 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 333-361), (C-Term) antibodyTIMD4 适用: 人 WB 宿主: 兔 Polyclonal RB40431 unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (C-Term) antibodyTIMD4 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 25-130) antibodyTIMD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) antibodyTIMD4 适用: 小鼠 ELISA, FACS, IP, in vivo 宿主: 兔 Chimeric 5G3 unconjugated Recombinant Antibody
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
Target Species of Antibody: Mouse
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
-
- 抗原
- TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
- 别名
- TIMD4 / TIM4 / TIM-4 (TIMD4 产品)
- 背景
-
Name/Gene ID: TIMD4
Synonyms: TIMD4, SMUCKLER, TIM-4, T-cell membrane protein 4, TIM4, TIMD-4, TIM 4 - 基因ID
- 91937
- 途径
- Cancer Immune Checkpoints
-
