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SIGLEC7 抗体

This 小鼠 单克隆 anti-SIGLEC7 antibody (Clone S7-7) specifically detects SIGLEC7 in WB, ELISA, IP, FACS, Func 和 DNA Mic. The antibody is reactive with 人, 猕猴 和 猴 samples.
产品编号 ABIN1819168
发货至: 中国
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Quick Overview for SIGLEC7 抗体 (ABIN1819168)

抗原

See all SIGLEC7 抗体
SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

适用

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人, 猕猴, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This SIGLEC7 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Functional Studies (Func), DNA Microscopy (DNA Mic)

克隆位点

S7-7
  • 特异性

    Recognizes human Sialic acid-binding Ig-like lectin 7, otherwise known as CD328, a putative adhesion molecule and member of the Ig superfamily, predominantly expressed by both resting and activated natural killer (NK) cells, and also at lower levels by monocytes, granulocytes, monocyte-derived macrophages and dendritic cells, and a small population of CD8+ memory T cells. Classified as a CD33-related Siglec, Siglec-7 preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid, and acts as a novel inhibitory receptor for NK cells, mediating the inhibition of NK cell cytotoxicity, and implicated in the regulation of NK cell and T cell activation, and hematopoiesis. Clone S7.7 is a blocking antibody see for details, and has been shown to recognize Siglec-7 in Rhesus monkey see for details.

    纯化方法

    Protein G purified

    内毒素水平

    Low Endotoxin

    免疫原

    Siglec-7 3T3 transfected cells.

    Type of Immunogen: Cells

    亚型

    IgG1
  • 应用备注

    Approved: ELISA, Flo, Func, IP, WB

    Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

    别名

    SIGLEC7 / CD328

    背景

    Name/Gene ID: SIGLEC7
    Family: Immunoglobulin

    Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein

    基因ID

    27036
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