CD276 抗体 (AA 1-242) (PE)
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- 抗原 See all CD276 抗体
- CD276
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抗原表位
- AA 1-242
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD276 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Recognizes mouse CD276, otherwise known as B7-H3, a ubiquitously expressed transmembrane glycoprotein and member of the B7 family of co-stimulatory molecules, which acts as both a positive and negative regulator of T-cell-mediated immune responses. CD276 is highly expressed in bone during embryogenesis, and can be induced on dendritic cells and monocytes by inflammatory cytokines. CD276 has been implicated in the development of acute and chronic transplant rejection, and is reported to have therapeutic potential as a regulator of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy. In mice, CD276 has been linked with the development of pathogenic Th2 cells during the induction phase of allergic asthma, see for details.
- 纯化方法
- Protein G purified
- 免疫原
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Mouse IgG2a Fc-CD276 (aa 1-242).
Type of Immunogen: Fusion protein - 克隆位点
- MJ8
- 亚型
- IgG2b
- Top Product
- Discover our top product CD276 Primary Antibody
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- 应用备注
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Approved: Flo
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Mouse
- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
- Distilled water
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze. Protect from light.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C. Do not freeze. Protect from light.
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- 抗原
- CD276
- 别名
- CD276 / B7-H3 (CD276 产品)
- 背景
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Name/Gene ID: CD276
Synonyms: CD276, 4Ig-B7-H3, B7 homolog 3, B7-H3, CD276 antigen, CD276 Molecule, Costimulatory molecule, B7H3, B7RP-2 - 基因ID
- 80381
- UniProt
- Q5ZPR3
- 途径
- Cancer Immune Checkpoints
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