EGFR 抗体 (Extracellular Domain) (PE)
Quick Overview for EGFR 抗体 (Extracellular Domain) (PE) (ABIN181809)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody recognises the epidermal growth factor receptor (EGFR). This antibody binds to epitope B from EGFR (1, 2).Aff. Const.:6.7 x 10e-9 M
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Extracellular domain of human EGF-receptor from head and neck carcinoma.
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亚型
- IgG2a
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应用备注
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Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1.0 mL distilled water
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缓冲液
- PBS containing 1 % BSA and 5 % Bovine Serum Albumin
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储存液
- Sodium azide
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注意事项
- Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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别名
- EGFR / ERBB1
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背景
- EGFR is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
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基因ID
- 1956
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NCBI登录号
- NP_005219
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UniProt
- P00533
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
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