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EGFR 抗体 (Extracellular Domain) (PE)

EGFR 适用: 人 FACS 宿主: 大鼠 Monoclonal ICR10 PE
产品编号 ABIN181809
发货至: 中国
  • 抗原 See all EGFR 抗体
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    抗原表位
    • 39
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    Extracellular Domain
    适用
    • 750
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    宿主
    • 580
    • 167
    • 14
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    • 1
    • 1
    大鼠
    克隆类型
    • 542
    • 238
    • 2
    单克隆
    标记
    • 412
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    This EGFR antibody is conjugated to PE
    应用范围
    • 535
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    • 1
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises the epidermal growth factor receptor (EGFR). This antibody binds to epitope B from EGFR (1, 2).Aff. Const.:6.7 x 10e-9 M
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Extracellular domain of human EGF-receptor from head and neck carcinoma.
    克隆位点
    ICR10
    亚型
    IgG2a
    Top Product
    Discover our top product EGFR Primary Antibody
  • 应用备注
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.0 mL distilled water
    缓冲液
    PBS containing 1 % BSA and 5 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    EGFR (Epidermal Growth Factor Receptor (EGFR))
    别名
    EGFR / ERBB1 (EGFR 产品)
    背景
    EGFR is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
    基因ID
    1956
    NCBI登录号
    NP_005219
    UniProt
    P00533
    途径
    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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