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EPH Receptor A4 抗体 (C-Term)

The 兔 多克隆 anti-EPH Receptor A4 antibody (ABIN181176) specifically detects EPH Receptor A4 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN181176
发货至: 中国
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Quick Overview for EPH Receptor A4 抗体 (C-Term) (ABIN181176)

抗原

See all EPH Receptor A4 (EPHA4) 抗体
EPH Receptor A4 (EPHA4)

适用

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宿主

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克隆类型

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多克隆

标记

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This EPH Receptor A4 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects Ephrin Type A Receptor 4.

    纯化方法

    Immunoaffinity chromatography

    免疫原

    EPHA4 antibody was raised against synthetic peptide from C-terminal domain of human EPHA4. Genename: EPHA4
  • 应用备注

    Immunohistochemistry: 18 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS containing 0.009 % sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原

    EPH Receptor A4 (EPHA4)

    别名

    EPHA4

    背景

    Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5 but binds more poorly to ephrin-A2 and -A3. Eph receptor A4 may play a role in a signal transduction process involved in hindbrain pattern formation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: Ephrin type-A receptor 4, HEK8, Receptor protein-tyrosine kinase HEK8, SEK, TYRO1, Tyrosine-protein kinase TYRO1, Tyrosine-protein kinase receptor SEK

    基因ID

    2043

    NCBI登录号

    NP_004429

    UniProt

    P54764

    途径

    RTK signaling
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