Complement C4A/C4B 抗体
This anti-Complement C4A/C4B antibody is a 小鼠 单克隆 antibody detecting Complement C4A/C4B in EIA, IHC (fro) 和 FACS. Suitable for 人.
产品编号 ABIN181130
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Complement C4A/C4B 抗体 (ABIN181130)
抗原
Complement C4A/C4B
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
克隆位点
057-51-5-1-6
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特异性
- This antibody recognises a neoantigen on the secreted protein complement component 4d (C4d).
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产品特性
- Synonyms: Complement component 4, CPAMD2, CPAMD3, Acidic complement C4, Basic complementC4
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- Purified human C4d. Genename: C4d
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亚型
- IgG1
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anti-Complement C4A/C4B (Internal Region) antibody
适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement C4A/C4B (Center) antibody适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0mg/mL
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缓冲液
- Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Complement C4A/C4B
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背景
- The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated. Single site cleavage of the C4bs alpha chain by Factor I forms iC4b and blocks C3 convertase, inhibiting opsonisation and activation of the classical pathway. This requires C4 binding protein or CR1 as a cofactor. iC4b is further degraded into C4d and C4c. The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation. C4 has been linked to susceptibility to systemic lupus erythematosous.Synonyms: Acidic complement C4, Basic complement C4, CPAMD2, CPAMD3, Complement component 4
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基因ID
- 720
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UniProt
- P0C0L4
抗原
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