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Complement C4A/C4B 抗体

适用: 人 EIA 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN113341
发货至: 中国
  • 抗原
    Complement C4A/C4B
    适用
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 4
    • 4
    • 2
    小鸡
    克隆类型
    • 6
    • 4
    多克隆
    标记
    • 10
    非结合性
    应用范围
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    特异性
    This antibody was found not to cross-react with Human C3a. The antibody was generated against the carboxy-terminal neoepitope which is not exposed on C4, allowing discrimination between C4 and C4a.
    纯化方法
    Affinity Chromatography
    免疫原
    Synthetic peptide coupled to carreir protein.
  • 应用备注
    ELISA: The titer with native human C4a was > 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.2, 0.09 % Sodium Azide, 30 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • 抗原
    Complement C4A/C4B
    别名
    C4 antibody, C4-1 antibody, C4b antibody, complement component 4A (Rodgers blood group) antibody, C4a antibody
    背景
    The complement system is part of the innate immune system representing humoral defence. Activation of the complement cascade via the the alternative pathway liberates several biologically active by-products, among them the anaphylatoxin C4a. Measurement of C4a (and C3a) in plasma or other body fluids can yield important clues about the pathological, and particularly also the inflammatory status of an organism. In serum, C4a activity is under control of the carboxypeptidase N. This enzyme rapidly cuts off the C-terminal arginine, thereby generating C4adesArg. This degradation product C4adesArg remains relatively stable until it is cleared from the circulation.Synonyms: Acidic complement C4, Basic complement C4, CPAMD2, CPAMD3, Complement component 4
    基因ID
    720
    NCBI登录号
    NP_009224
    UniProt
    P0C0L4
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