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Integrin beta 2 抗体 (FITC)

The FITC-conjugated 小鼠 单克隆 anti-Integrin beta 2 antibody (Clone PNK-I) (ABIN180771) specifically detects Integrin beta 2 in FACS. The antibody is reactive with Pig samples.
产品编号 ABIN180771
发货至: 中国
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Quick Overview for Integrin beta 2 抗体 (FITC) (ABIN180771)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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Pig

宿主

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小鼠

克隆类型

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单克隆

标记

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This Integrin beta 2 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

PNK-I
  • 特异性

    This antibody recognises the porcine homologue of human CD18. Other species not tested.

    产品特性

    Synonyms: Integrin beta-2, MFI7, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunitbeta, Complement receptor C3 subunit beta

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    Porcine large granular lymphocytes. Spleen cells from immunised Balb/c mice were fusedwith cells of the mouse P3-X63-Ag8. 653 myeloma cell line. Genename: CD18a

    亚型

    IgG1
  • 应用备注

    Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    CD18 / ITGB2

    背景

    CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7

    基因ID

    396943

    UniProt

    P53714

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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