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NGFR 抗体 (N-Term)

Name: NGFR 抗体 (N-Term)
SKU: ABIN180341
Availability: OutOfStock

NGFR 适用: 人, 兔, Cat, 雪貂, 猴 WB, FACS, IF, IHC (p), IP 宿主: 小鼠 Monoclonal NGFR5 unconjugated

(4 references)

产品编号 ABIN180341

发货至: 中国

Datasheet as PDF

抗原 See all NGFR 抗体

NGFR (Nerve Growth Factor Receptor (NGFR))
抗原表位
16

8

8

8

6

5

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-160, N-Term
适用
155

65

57

27

26

25

24

20

11

5

4

3

3

3

2

2

2

1

1
人, 兔, Cat, 雪貂, 猴
宿主
87

75

4

1
小鼠
Compatible Secondaries
克隆类型
93

74
单克隆
标记
85

14

11

6

5

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This NGFR antibody is un-conjugated
应用范围
91

82

55

47

41

27

27

18

16

15

15

12

7

6

4

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

特异性

This antibody recognizes CD271/NGFR, a transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within amino acids 1-160.
Cellular Localization: Cell Surface, Cytoplasmic.

交叉反应（详细）

Species reactivity (tested):Human, Monkey (Cebus apella, Macaca fascicularis, mulatta, and nemestrina), Baboon (Papio anubis and Cynocephalus), Cat, Rabbit, and Ferret.

产品特性

Synonyms: TNFRSF16, Tumor necrosis factor receptor superfamily member 16

纯化方法

Protein-A affinity chromatography

免疫原

NGFR (75kD) from A875 Melanoma Cells.

克隆位点

NGFR5

亚型

IgG1

Top Product

Discover our top product NGFR Primary Antibody
anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR 适用: 人, 大鼠, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 大鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated

anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibody
NGFR 适用: 人 IHC, Diff, StM 宿主: 小鼠 Monoclonal NGFR-1964 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular), (Stalk Region) antibody
NGFR 适用: 人, 大鼠, 小鼠 WB, FACS, IF, IHC, ICC, IP, LCI 宿主: 兔 Polyclonal unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, Non-Human Primate IHC, Diff, StM 宿主: 兔 Monoclonal NGFR-1997R unconjugated Recombinant Antibody

anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibody
NGFR 适用: 人 IHC, Diff, StM 宿主: 小鼠 Monoclonal rNGFR-1965 unconjugated Recombinant Antibody

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, Non-Human Primate, 兔, Cat, 雪貂 WB, FACS, IHC (p), ICC, IP, CyTOF 宿主: 小鼠 Monoclonal NGFR5 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2F1C2 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, 小鼠 WB, IF, ELISA, IHC 宿主: 小鼠 Monoclonal 8G3G10 unconjugated

anti-Nerve Growth Factor Receptor (NGFR) antibody
NGFR 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 8G3G10 unconjugated

应用备注

Flow Cytometry. Immunocytochemistry. Inhibits Binding of NGF to Melanoma Cells (see Ref.1, use antibody without azide: ABIN180340). Not suitable for Western Blotting andImmunohistochemistry. Recommended Positive Control: Melanoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS, pH ~7.4, 15 mM Sodium Azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at 2-8 °C for up to one month or in aliquots at -20 °C for longer. Avoid repeated freezethaw cycles!
Shelf life: one year from despatch.

有效期

12 months
Molina-Ruiz, Cerroni, Kutzner, Requena: "Immunohistochemistry in the diagnosis of cutaneous bacterial infections." in: The American Journal of dermatopathology, Vol. 37, Issue 3, pp. 179-93; quiz 194-6, (2015) (PubMed).

Alpers, Hudkins, Ferguson, Johnson, Schatteman, Bothwell: "Nerve growth factor receptor expression in fetal, mature, and diseased human kidneys." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 69, Issue 6, pp. 703-13, (1994) (PubMed).

Schatteman, Gibbs, Lanahan, Claude, Bothwell: "Expression of NGF receptor in the developing and adult primate central nervous system." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 8, Issue 3, pp. 860-73, (1988) (PubMed).

Marano, Dietzschold, Earley, Schatteman, Thompson, Grob, Ross, Bothwell, Atkinson, Koprowski: "Purification and amino terminal sequencing of human melanoma nerve growth factor receptor." in: Journal of neurochemistry, Vol. 48, Issue 1, pp. 225-32, (1987) (PubMed).
抗原

NGFR (Nerve Growth Factor Receptor (NGFR))

别名

CD271 / NGFR (NGFR 产品)

背景

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.Synonyms: TNFRSF16, Tumor necrosis factor receptor superfamily member 16

分子量

75 kDa

基因ID

4804

UniProt

P08138

途径

NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding