EPH Receptor A2 抗体
Quick Overview for EPH Receptor A2 抗体 (ABIN179724)
抗原
See all EPH Receptor A2 (EPHA2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Anti-human EphA2
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纯化方法
- Protein G
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免疫原
- genetic immunisation with cDNA encoding human EphA2
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亚型
- IgG1
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应用备注
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Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. -
说明
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Synonyms: Eph receptor tyrosine kinase A2
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限制
- 仅限研究用
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浓度
- 2 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C
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储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- EPH Receptor A2 (EPHA2)
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别名
- EPHA2
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背景
- EphA2 (Ephrin receptor tyrosine kinase A2) belongs to the Ephrin tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells. Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis. The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it represent an attractive potential target for drug design.
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UniProt
- P29317
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途径
- RTK signaling
抗原
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