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EPH Receptor A2 抗体

This 小鼠 单克隆 anti-EPH Receptor A2 antibody (Clone Kalpha-5H5) specifically detects EPH Receptor A2 in FACS, IF 和 cELISA. The antibody is reactive with 人 samples.
产品编号 ABIN179724
发货至: 中国
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Quick Overview for EPH Receptor A2 抗体 (ABIN179724)

抗原

See all EPH Receptor A2 (EPHA2) 抗体
EPH Receptor A2 (EPHA2)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This EPH Receptor A2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Cell-ELISA (cELISA)

克隆位点

Kalpha-5H5
  • 特异性

    Anti-human EphA2

    纯化方法

    Protein G

    免疫原

    genetic immunisation with cDNA encoding human EphA2

    亚型

    IgG1
  • 应用备注

    Flow cytometry: 1.2 µg/10^6 cells
    Immunofluorescence: 1 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.

    说明

    Synonyms: Eph receptor tyrosine kinase A2

    限制

    仅限研究用
  • 浓度

    2 mg/mL

    缓冲液

    PBS, pH 7.2

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C

    储存方法

    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原

    EPH Receptor A2 (EPHA2)

    别名

    EPHA2

    背景

    EphA2 (Ephrin receptor tyrosine kinase A2) belongs to the Ephrin tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells. Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis. The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it represent an attractive potential target for drug design.

    UniProt

    P29317

    途径

    RTK signaling
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