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LRRC32 抗体 (AA 296-308)

LRRC32 适用: 人 FACS 宿主: 小鼠 Monoclonal 227G6 unconjugated
产品编号 ABIN1742450
发货至: 中国
  • 抗原 See all LRRC32 抗体
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 296-308
    适用
    • 26
    • 10
    • 9
    • 1
    宿主
    • 20
    • 12
    • 1
    • 1
    小鼠
    克隆类型
    • 21
    • 13
    单克隆
    标记
    • 18
    • 7
    • 4
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    应用范围
    • 16
    • 16
    • 14
    • 6
    • 4
    • 3
    • 2
    • 1
    Flow Cytometry (FACS)
    特异性
    Specific for GARP.
    纯化方法
    purified IgG. Azide was added before lyophilization.
    免疫原
    Synthetic peptide (aa 296-308 of human GARP) coupled to KLH via N-terminal added cysteine.
    克隆位点
    227G6
    亚型
    IgG3
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • 应用备注
    WB: not recommended
    IP: not tested yet
    ICC: not tested yet
    IHC: not tested yet
    FACS: 1 : 100 up to 1 : 1000
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    For reconstitution add 100 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
    缓冲液
    PBS, 0.02% sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.
    储存条件
    -20 °C
    储存方法
    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Cuende, Liénart, Dedobbeleer, van der Woning, De Boeck, Stockis, Huygens, Colau, Somja, Delvenne, Hannon, Baron, Dumoutier, Renauld, De Haard, Saunders, Coulie, Lucas: "Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo." in: Science translational medicine, Vol. 7, Issue 284, pp. 284ra56, (2015) (PubMed).

    Rappl, Pabst, Riemann, Schmidt, Wickenhauser, Schütte, Hombach, Seliger, Grohé, Abken: "Regulatory T cells with reduced repressor capacities are extensively amplified in pulmonary sarcoid lesions and sustain granuloma formation." in: Clinical immunology (Orlando, Fla.), Vol. 140, Issue 1, pp. 71-83, (2011) (PubMed).

    Probst-Kepper, Geffers, Kröger, Viegas, Erck, Hecht, Lünsdorf, Roubin, Moharregh-Khiabani, Wagner, Ocklenburg, Jeron, Garritsen, Arstila, Kekäläinen, Balling, Hauser, Buer, Weiss: "GARP: a key receptor controlling FOXP3 in human regulatory T cells." in: Journal of cellular and molecular medicine, Vol. 13, Issue 9B, pp. 3343-57, (2010) (PubMed).

  • 抗原
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    别名
    GARP (LRRC32 产品)
    别名
    D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody
    背景
    Synonyms: LRRC 32
    途径
    Activated T Cell Proliferation
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