LRRC32 抗体 (APC)
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- 抗原 See all LRRC32 抗体
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LRRC32 antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
- 克隆位点
- GARP5
- 亚型
- IgG1
- Top Product
- Discover our top product LRRC32 Primary Antibody
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anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 162-405) antibody
LRRC32 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 234-260) antibodyLRRC32 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 234-260) antibodyLRRC32 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB18218 unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 400-643) antibodyLRRC32 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 250-300) antibodyLRRC32 适用: 人, 小鼠, 大鼠, 猴 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) antibodyLRRC32 适用: 人 WB 宿主: 小鼠 Monoclonal GARP5 unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 301-500) antibodyLRRC32 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 20-627) antibody (PE)LRRC32 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal Plato-1 PE
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 20-627) antibody (FITC)LRRC32 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal Plato-1 FITC
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 23-612) antibodyLRRC32 适用: 人 WB 宿主: 小鼠 Monoclonal 50G10 unconjugated
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- 应用备注
- This antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 μLper test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.
- 说明
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5 uL (0.5 ug)/test
- 限制
- 仅限研究用
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- 缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C protected from light
- 有效期
- 12 months
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- 抗原
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- 别名
- GARP (LRRC32 产品)
- 别名
- D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody
- 背景
- The GARP5 antibody reacts with human GARP, also known as LRRC32 or Garpin, an 80 kDa transmembrane protein which acts as a receptor for the latent form of TGF-beta 1 (pro-TGF-beta), preventing its secretion. Specifically, GARP is reported to associate with the pro-domain of TGF-beta 1, known as latency-associated peptide (LAP), which must be cleaved to release the biologically active cyto- kine. The putative role of GARP in sequestering the TGF-beta is important for regulating its activity, as TGF-beta signaling is involved in development and function of Th17, Treg and many other immune cell types. GARP expression has been shown on platelets and at high levels on Foxp3+ Treg cells, where it is proposed to be a phenotypic identifier for activated human Treg cells. The GARP5 antibody may be used for analysis of human GARP by flow cytometry, immunoprecipitation and Western blotting.
- 基因ID
- 2615
- 途径
- Activated T Cell Proliferation
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