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LRRC32 抗体

LRRC32 适用: 人 WB 宿主: 小鼠 Monoclonal GARP5 unconjugated
产品编号 ABIN1981876
发货至: 中国
  • 抗原 See all LRRC32 抗体
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    适用
    • 26
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    • 1
    宿主
    • 20
    • 12
    • 1
    • 1
    小鼠
    克隆类型
    • 21
    • 13
    单克隆
    标记
    • 18
    • 7
    • 4
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    应用范围
    • 17
    • 15
    • 14
    • 6
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    • 1
    Western Blotting (WB)
    特异性
    The mouse monoclonal antibody GARP5 recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Purified human sGARP protein
    克隆位点
    GARP5
    亚型
    IgG1
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • 应用备注
    Western blotting: Recommended dilution: 1-2 μg/mL, positive control: human thrombocytes, reducing conditions
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Do not use after expiration date stamped on vial label.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Wang, Zhu, Dong, Shi, Lu, Springer: "GARP regulates the bioavailability and activation of TGF?." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1129-39, (2012) (PubMed).

  • 抗原
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    别名
    GARP / LRRC32 (LRRC32 产品)
    别名
    D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody
    背景
    Leucine rich repeat containing 32,GARP (glycoprotein A repetitions predominant protein), also known as garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.,GARP, D11S833E
    基因ID
    2615
    UniProt
    Q14392
    途径
    Activated T Cell Proliferation
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