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RAB27A 抗体 (AA 1-221)

Cited in 2+ publications. This 兔 多克隆 anti-RAB27A antibody specifically detects RAB27A in WB, IP 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1742354
发货至: 中国
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Quick Overview for RAB27A 抗体 (AA 1-221) (ABIN1742354)

抗原

See all RAB27A 抗体
RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

适用

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  • 5
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人, 小鼠, 大鼠

宿主

  • 47
  • 12
  • 3
  • 2

克隆类型

  • 40
  • 24
多克隆

标记

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This RAB27A antibody is un-conjugated

应用范围

  • 49
  • 26
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  • 12
  • 5
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 抗原表位

    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-221

    原理

    Rabbit anti-Rab27A antibody

    特异性

    Specific for rab 27A

    交叉反应 (详细)

    Reacts with: rat (P23640), mouse (Q9ERI2), human (P51159). Other species not tested yet.

    纯化方法

    affinity purified

    免疫原

    Recombinant protein corresponding to AA 1 to 221 from rat Rab27A (UniProt Id: P23640)
  • 应用备注

    WB:1 : 1000 , IP:yes ICC:not tested yet IHC:not tested yet IHC-P:1 : 2000,

    说明

    Only the non-conserved C-terminal part of the protein was used for affinity purification to achieve specificity.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

    缓冲液

    PBS. Albumin was added for stabilization.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,-80 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin was added for stabilization. Do not freeze!
  • Hou, Ernst, Stuenkel, Lentz, Williams: "Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125596, (2015) (PubMed).

    Lovis, Roggli, Laybutt, Gattesco, Yang, Widmann, Abderrahmani, Regazzi: "Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction." in: Diabetes, Vol. 57, Issue 10, pp. 2728-36, (2008) (PubMed).

  • 抗原

    RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

    别名

    Rab27A

    背景

    Synonyms: Rab27, pancreas, insulin granules, secretory vesicles, pancreatic islands

    Antigen Information: K.O. Rab27 proteins are members of the Rab family responsible for melanosomal transport and hormone secretion

    UniProt

    P23640

    途径

    Peptide Hormone Metabolism
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