PINK1 抗体 (Internal Region)
Quick Overview for PINK1 抗体 (Internal Region) (ABIN1738106)
抗原
See all PINK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-500, Internal Region
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特异性
- Reacts with human and mouse PINK1 protein
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纯化方法
- Antigen affinity purified
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免疫原
- A genomic peptide made to an internal region of the human PINK1 protein (within residues 350-500).
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亚型
- IgG
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anti-PTEN Induced Putative Kinase 1 (PINK1) (Internal Region) antibody
Verified PINK1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-273) antibodyPINK1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3A9F8 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) antibodyPINK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal 38CT20-8-5 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-273) antibodyPINK1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5F2B11 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibodyPINK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S4-15 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (HRP)PINK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S4-15 HRP
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (FITC)PINK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S4-15 FITC
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (Biotin)PINK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S4-15 Biotin
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (PE)PINK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S4-15 PE
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (PerCP)PINK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S4-15 PerCP
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF1:500-1:1000, IHC1:100, IHC-P 1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.17 mg/mL
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缓冲液
- PBS, Sodium azide 0.05 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 6 months
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- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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别名
- PINK1
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背景
- PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers.It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease. It protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.
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基因ID
- 65018
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UniProt
- Q9BXM7
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途径
- Autophagy
抗原
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