F12 抗体
Quick Overview for F12 抗体 (ABIN1734212)
抗原
See all F12 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with human F12 / Factor XII
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交叉反应 (详细)
- Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma.
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纯化方法
- Purified
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免疫原
- Activated human Factor XII (F XIIa) purified from plasma.
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亚型
- IgG
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应用备注
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Working dilution: IHC-P (5 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM HEPES, pH 7.4, 0.15 M NaCl, 50 % glycerol.
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储存条件
- 4 °C/-20 °C
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储存方法
- Long term: -20°C, Short term: +4°C. Avoid repeat freeze-thaw cycles.
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- F12 (Coagulation Factor XII (F12))
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别名
- F12 / Factor XII
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背景
- Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
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途径
- Complement System
抗原
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