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ERK1/2 抗体

This 兔 多克隆 anti-ERK1/2 antibody specifically detects ERK1/2 in WB. The antibody is reactive with 人, 小鼠, 小鸡, 非洲爪蟾, 哺乳动物 和 Drosophila melanogaster samples.
产品编号 ABIN1734127
发货至: 中国
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Quick Overview for ERK1/2 抗体 (ABIN1734127)

抗原

See all ERK1/2 (MAPK1/3) 抗体
ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

适用

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人, 小鼠, 小鸡, 非洲爪蟾, 哺乳动物, Drosophila melanogaster

宿主

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克隆类型

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多克隆

标记

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This ERK1/2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    Reacts with human Erk1 and Erk2. Cross-reacts with mouse, rat, chicken, sheep, bovine, drosophila and xenopus protein.

    纯化方法

    Serum

    免疫原

    35 amino acid synthetic peptide corresponding to ERK1 conjugated to KLH.

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    WB1:5000

    Positive control: HeLa cell

    限制

    仅限研究用
  • 注意事项

    Dilute in PBS or medium which is identical to that used in the assay system.

    储存条件

    4 °C/-20 °C

    储存方法

    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

    有效期

    6 months
  • 抗原

    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

    别名

    Erk1 + Erk2

    背景

    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

    Mitogen-activated protein kinase 3 & Mitogen-activated protein kinase 1 Extracellular signal-regulated kinase 1 & Extracellular signal-regulated kinase 3 ERK-1 & ERK-2 Gene name: MAPK3, MAPK1

    UniProt

    P27361, P28482
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