Axin 抗体 (C-Term)
Quick Overview for Axin 抗体 (C-Term) (ABIN1732156)
抗原
See all Axin (AXIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with the C-terminus part of human AXIN1
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交叉反应
- 小鼠, 牛, 犬, 大鼠
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交叉反应 (详细)
- Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
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纯化方法
- Antigen affinity purified
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免疫原
- Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
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应用备注
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Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Minimize freezing and thawing.
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- Axin (AXIN1) (Axin 1 (AXIN1))
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别名
- AXIN1
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背景
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
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UniProt
- O15169
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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