Axin 抗体 (C-Term)
Quick Overview for Axin 抗体 (C-Term) (ABIN1732155)
抗原
See all Axin (AXIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with human AXIN1
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纯化方法
- Antigen affinity purified
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免疫原
- 14 amino acid peptide near the carboxy terminus of human AXIN1
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亚型
- IgG
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应用备注
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Working dilution: IHC - P (5 μg/mL), WB (1 - 2 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, Sodium azide 0.02 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
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- Axin (AXIN1) (Axin 1 (AXIN1))
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别名
- AXIN1
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背景
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
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UniProt
- O15169
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途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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