BDNF 抗体 (AA 19-248)
Quick Overview for BDNF 抗体 (AA 19-248) (ABIN1724944)
抗原
See all BDNF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 19-248
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原理
- BDNF Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human BDNF (AA: 19-248) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder." in: PLoS ONE, Vol. 7, Issue 8, pp. e42676, (2012) (PubMed).
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Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder." in: PLoS ONE, Vol. 7, Issue 8, pp. e42676, (2012) (PubMed).
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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别名
- BDNF
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背景
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The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
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分子量
- 27.8 kDa
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基因ID
- 627
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UniProt
- P23560
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途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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