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BDNF 抗体 (AA 19-248)

This anti-BDNF antibody is a 小鼠 单克隆 antibody detecting BDNF in WB, ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1724944
发货至: 中国

Quick Overview for BDNF 抗体 (AA 19-248) (ABIN1724944)

抗原

See all BDNF 抗体
BDNF (Brain-Derived Neurotrophic Factor (BDNF))

适用

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宿主

  • 136
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  • 6
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  • 2
小鼠

克隆类型

  • 138
  • 66
单克隆

标记

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This BDNF antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

克隆位点

3D9C5
  • 抗原表位

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    AA 19-248

    原理

    BDNF Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human BDNF (AA: 19-248) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yoshida, Ishikawa, Niitsu, Nakazato, Watanabe, Shiraishi, Shiina, Hashimoto, Kanahara, Hasegawa, Enohara, Kimura, Iyo, Hashimoto: "Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder." in: PLoS ONE, Vol. 7, Issue 8, pp. e42676, (2012) (PubMed).

  • 抗原

    BDNF (Brain-Derived Neurotrophic Factor (BDNF))

    别名

    BDNF

    背景

    The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.

    分子量

    27.8 kDa

    基因ID

    627

    UniProt

    P23560

    途径

    RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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