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CSF1R 抗体 (AA 344-497)

This anti-CSF1R antibody is a 小鼠 单克隆 antibody detecting CSF1R in ELISA, IHC 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724925
发货至: 中国

Quick Overview for CSF1R 抗体 (AA 344-497) (ABIN1724925)

抗原

See all CSF1R 抗体
CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

适用

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宿主

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  • 3
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  • 2
小鼠

克隆类型

  • 207
  • 47
  • 2
单克隆

标记

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This CSF1R antibody is un-conjugated

应用范围

  • 161
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ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

6B9B9
  • 抗原表位

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    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
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    • 1
    AA 344-497

    原理

    CSF1R Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CSF1R (AA: 344-497) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Morandi, Barbetti, Riverso, Dello Sbarba, Rovida: "The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines." in: PLoS ONE, Vol. 6, Issue 11, pp. e27450, (2011) (PubMed).

    Kitagawa, Gouda, Kirii, Sugiyama, Ishihama, Fujii, Narumi, Akita, Yokota: "Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase." in: Journal of biochemistry, Vol. 151, Issue 1, pp. 47-55, (2011) (PubMed).

  • 抗原

    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

    别名

    CSF1R

    背景

    The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.



    分子量

    108 kDa

    基因ID

    1436

    UniProt

    P07333

    途径

    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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