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MCAM 抗体 (AA 84-189)

MCAM 适用: 人 IHC, WB, ELISA 宿主: 小鼠 Monoclonal 6C3F1 unconjugated
产品编号 ABIN1724898
发货至: 中国
  • 抗原 See all MCAM 抗体
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    抗原表位
    • 16
    • 13
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 84-189
    适用
    • 128
    • 48
    • 47
    • 15
    • 14
    • 9
    • 9
    • 8
    • 6
    • 2
    宿主
    • 96
    • 56
    • 1
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 87
    • 69
    单克隆
    标记
    • 76
    • 14
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCAM antibody is un-conjugated
    应用范围
    • 92
    • 72
    • 66
    • 44
    • 20
    • 20
    • 18
    • 12
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. coli.
    克隆位点
    6C3F1
    亚型
    IgG1
    Top Product
    Discover our top product MCAM Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Wang, Yan: "CD146, a multi-functional molecule beyond adhesion." in: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).

    Jouve, Despoix, Espeli, Gauthier, Cypowyj, Fallague, Schiff, Dignat-George, Vély, Leroyer: "The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells." in: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2571-9, (2013) (PubMed).

  • 抗原
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    别名
    MCAM (MCAM 产品)
    别名
    CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
    背景

    Description: The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during , embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration ,

    Aliases: CD146, MUC18

    分子量
    71.6 kDa
    基因ID
    4162
    HGNC
    4162
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