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CD25 抗体 (AA 34-139)

Cited in 2+ publications. This anti-CD25 antibody is a 小鼠 单克隆 antibody detecting CD25 in WB, IHC, ELISA 和 ICC. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN1724861
发货至: 中国
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Quick Overview for CD25 抗体 (AA 34-139) (ABIN1724861)

抗原

See all CD25 (IL2RA) 抗体
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

适用

  • 240
  • 126
  • 38
  • 11
  • 10
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, 猴

宿主

  • 175
  • 98
  • 90
  • 20
  • 2
  • 2
  • 2
  • 1
小鼠

克隆类型

  • 309
  • 76
  • 4
单克隆

标记

  • 153
  • 40
  • 30
  • 29
  • 25
  • 9
  • 6
  • 5
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  • 4
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  • 2
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  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CD25 antibody is un-conjugated

应用范围

  • 244
  • 91
  • 80
  • 56
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  • 31
  • 22
  • 17
  • 16
  • 8
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  • 1
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  • 1
  • 1
  • 1
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  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

克隆位点

1B5D12
  • 抗原表位

    • 23
    • 16
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 34-139

    原理

    IL2RA Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human IL2RA (AA: 34-139) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shvidel, Braester, Bairey, Rahimi-Levene, Herishanu, Tadmor, Klepfish, Ruchlemer, Shtalrid, Berrebi, Polliack: "Cell surface expression of CD25 antigen (surface IL-2 receptor α-chain) is not a prognostic marker in chronic lymphocytic leukemia: results of a retrospective study of 281 patients." in: Annals of hematology, Vol. 91, Issue 10, pp. 1597-602, (2012) (PubMed).

    Sun, Wang, Zhu, Fang, Yu, Xu: "The interleukin-2 receptor α chain (CD25) plays an important role in regulating monocyte-derived CD40 expression during anti-porcine cellular responses." in: Transplantation proceedings, Vol. 44, Issue 4, pp. 1139-42, (2012) (PubMed).

  • 抗原

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    别名

    IL2RA

    背景

    The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.



    分子量

    30.8 kDa

    基因ID

    3559

    UniProt

    P01589

    途径

    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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