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MAPK14 抗体 (AA 299-360)

This anti-MAPK14 antibody is a 小鼠 单克隆 antibody detecting MAPK14 in WB, IHC, ELISA, ICC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1724830
发货至: 中国

Quick Overview for MAPK14 抗体 (AA 299-360) (ABIN1724830)

抗原

See all MAPK14 抗体
MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

适用

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宿主

  • 208
  • 44
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小鼠

克隆类型

  • 191
  • 67
单克隆

标记

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This MAPK14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

8G4D11
  • 抗原表位

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    AA 299-360

    原理

    MAPK14 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human MAPK14 (AA: 299-360) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/75

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Li, Zheng, Li, Ma: "Unfractionated heparin inhibits lipopolysaccharide-induced inflammatory response through blocking p38 MAPK and NF-?B activation on endothelial cell." in: Cytokine, Vol. 60, Issue 1, pp. 114-21, (2012) (PubMed).

    Chung, Tang, Sun, Chou, Yeh, Yu, Sun: "Galectin-1 promotes lung cancer progression and chemoresistance by upregulating p38 MAPK, ERK, and cyclooxygenase-2." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 15, pp. 4037-47, (2012) (PubMed).

  • 抗原

    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

    别名

    MAPK14

    背景

    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

    分子量

    41.3 kDa

    基因ID

    1432

    UniProt

    Q16539

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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