RET
适用: 人, 小鼠
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
应用备注
ELISA: 1/10000
限制
仅限研究用
状态
Liquid
缓冲液
Ascitic fluid containing 0.03 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Young, Anderson, Anderson: "Guidance cues involved in the development of the peripheral autonomic nervous system." in: Autonomic neuroscience : basic & clinical, Vol. 112, Issue 1-2, pp. 1-14, (2004) (PubMed).
Myers, Mulligan: "The RET receptor is linked to stress response pathways." in: Cancer research, Vol. 64, Issue 13, pp. 4453-63, (2004) (PubMed).
RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung