BCL3 抗体
Our Local Distributor
北京 101111
Quick Overview for BCL3 抗体 (ABIN1721461)
抗原
See all BCL3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Reacts with human and mouse Bcl-3.
-
纯化方法
- Purified
-
免疫原
- Recombinant mouse Bcl-3-6His.
-
亚型
- IgG1 lambda
-
-
-
-
应用备注
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB2 μg/mL. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS, pH 7.4
-
注意事项
- Dilute in PBS or medium that is identical to that used in the assay system.
-
储存条件
- -20 °C
-
储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
-
有效期
- 12 months
-
-
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
-
别名
- Bcl-3
-
背景
-
The gene encoding Bcl-3 was first identified as the gene altered in some cases of chronic B cell lymphocytic leukemia and was later found to belong to the IκB subfamily of inhibitors of NFκB transcription factors. Bcl-3 does not have DNA-binding activity, but it interacts with NFκB1 and NFκB2 which, when bound to DNA, repress gene transcription. Therefore, Bcl-3 may promote gene expression that is repressed by members of the NFκB family. Bcl-3 RNA is highly expressed in spleen and liver with lower levels of expression in heart, skeletal muscle, lung, kidney, and testes.
B-cell lymphoma 3 protein homolog, BCL-3 Gene name: Bcl3 -
UniProt
- Q9Z2F6
-
途径
- NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
抗原
-