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BCL3 抗体

This anti-BCL3 antibody is a 仓鼠 单克隆 antibody detecting BCL3 in WB, ELISA 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN1721461
发货至: 中国

Quick Overview for BCL3 抗体 (ABIN1721461)

抗原

See all BCL3 抗体
BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

适用

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人, 小鼠

宿主

  • 47
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仓鼠

克隆类型

  • 49
  • 10
单克隆

标记

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This BCL3 antibody is un-conjugated

应用范围

  • 45
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Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

150-3-5
  • 特异性

    Reacts with human and mouse Bcl-3.

    纯化方法

    Purified

    免疫原

    Recombinant mouse Bcl-3-6His.

    亚型

    IgG1 lambda
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB2 μg/mL.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.4

    注意事项

    Dilute in PBS or medium that is identical to that used in the assay system.

    储存条件

    -20 °C

    储存方法

    Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

    别名

    Bcl-3

    背景

    The gene encoding Bcl-3 was first identified as the gene altered in some cases of chronic B cell lymphocytic leukemia and was later found to belong to the IκB subfamily of inhibitors of NFκB transcription factors. Bcl-3 does not have DNA-binding activity, but it interacts with NFκB1 and NFκB2 which, when bound to DNA, repress gene transcription. Therefore, Bcl-3 may promote gene expression that is repressed by members of the NFκB family. Bcl-3 RNA is highly expressed in spleen and liver with lower levels of expression in heart, skeletal muscle, lung, kidney, and testes.

    B-cell lymphoma 3 protein homolog, BCL-3 Gene name: Bcl3

    UniProt

    Q9Z2F6

    途径

    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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