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TNFRSF11A 抗体 (AA 101-200)

Name: TNFRSF11A 抗体 (AA 101-200)
SKU: ABIN1714635
Availability: OutOfStock

This anti-TNFRSF11A antibody is a 兔多克隆 antibody detecting TNFRSF11A in WB, ELISA 和 IHC (p). Suitable for 小鼠和大鼠.

Paraformaldehyde-fixed, paraffin embedded mouse brain tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-RANK Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (TNFRSF11A 抗体 (AA 101-200))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat skeletal muscle tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-RANK Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (TNFRSF11A 抗体 (AA 101-200))

IHC (p)

2 images

产品编号 ABIN1714635

发货至: 中国

Quick Overview for TNFRSF11A 抗体 (AA 101-200) (ABIN1714635)

抗原

See all TNFRSF11A 抗体

TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

适用

小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This TNFRSF11A antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product TNFRSF11A Primary Antibody

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AA 101-200

交叉反应

小鼠, 大鼠

预测反应

Human,Sheep,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human RANK

亚型

IgG
anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 330-615) antibody
TNFRSF11A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 359-542) antibody
TNFRSF11A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-214) antibody
TNFRSF11A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 31-130) antibody
TNFRSF11A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G2 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 30-212) antibody
TNFRSF11A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 8H8B2 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 51-150) antibody
TNFRSF11A 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 330-615) antibody
TNFRSF11A 适用: 人 WB 宿主: 小鼠 Monoclonal D13 unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (AA 28-202) antibody
TNFRSF11A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) antibody
TNFRSF11A 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated

anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) (Extracellular Domain) antibody
TNFRSF11A 适用: 人, 小鼠 WB, FACS, IP 宿主: 小鼠 Monoclonal 64C1385-1 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

别名

Rank

背景

Synonyms: TNFRSF11A, CD 265, CD265, CD265 antigen, Activator of NFKB, EOF, FEO, mRANK, NFKB activator, ODFR, OFE, Osteoclast dferentiation factor receptor, PDB 2, Receptor activator of NF KB, receptor activator of nuclear factor kappa B, TNFRSF 11A, TNFSF11, TRANCE R, RANK receptor, TNR11_HUMAN.
Background: CD265 is a member of the tumor necrosis factor receptor (TNFR) family. Human and murine CD265 share 81 % amino acid identity in their extracellular domains. CD265 is widely expressed, with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. CD265 is also expressed in dendritic cells. RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of CD265. TRANCE (TNF-related activation-induced cytokines, also known as RANK ligand, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for CD265. The biological functions mediated by RANK include activation of NFkappaB and cjun N-terminal kinase, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis. The soluble form of CD265 is able to block TRANCE induced biological activity. The binding of anti-CD265 to cell surface CD265 triggers signal transduction and induces CD265 mediated bioactivity.

途径

NF-kappaB Signaling